Protein engineering remains an area of growing importance in pharmaceutical and
biotechnology research. Stabilization of a folded protein conformation is a frequent goal in …

Wounds are usually irregular in shapes, and accompanied with a series of disorders such as
hemorrhage and bacteria contamination. Here, we report a multifunctional hydrogel …

The storage of protein/peptide hormones within subcellular compartments and subsequent
release are crucial for their native function, and hence these processes are intricately …

Disulfide Bonds in Protein Folding and Stability | Oxidative Folding of Proteins: Basic
Principles, Cellular Regulation and Engineering | Books Gateway | Royal Society of Chemistry …

Polymer conjugated biologics form a multibillion dollar market, dominated by poly (ethylene
glycol)(PEG). Recent reports linked PEGs to immunological concerns, fueling the need for …

Atomistic molecular dynamics simulations of human serum albumin in the presence and
absence of disulfide bonds are presented. Simulations of 70 ns duration provide information …

BACKGROUND: Several alternative mechanisms have been proposed to explain why some
proteins are able to induce a TH2-biased and IgE-mediated immune response. These …

In Nature, numerous proteins have evolved to perform similar roles, such as mechanical
energy dispersion in different tissues. These biological macromolecules obtain their function …

In the present study, the alkaline protease has been extracted from the fish processing waste
using ammonium sulphate fractionation followed by ion-exchange chromatography on …

The role of protein structure in the reactivity of the four disulfide (S–S) bridges of lysozyme
was studied using Raman spectroscopy and molecular modelling. The experimental kinetics …