High throughput DNA sequencing methodology (next generation sequencing; NGS) has
rapidly evolved over the past 15 years and new methods are continually being …

Proteins are major building blocks of life. The protein content of a cell and an organism
provides key information for the understanding of biological processes and disease. Despite …

Label-free characterization of single biomolecules aims to complement fluorescence
microscopy in situations where labeling compromises data interpretation, is technically …

Highlights•Microfluidics is transforming traditional techniques in biotechnology.•Multi-step
experiments are automated on single device in parallel reactors.•Millions of parallel …

Detection of cancer markers is important for early diagnosis and timely treatment of cancer.
In this study, we fabricated a tailorable gold nanofilm-anodized aluminum oxide (Au-AAO) …

As analytical interests have become targeted on sensitive detection of objects of a tiny size
and volume, various fields in analytical chemistry have been developed to overcome …

Nanofluidic structures have over the last two decades emerged as a powerful platform for
detailed analysis of DNA on the kilobase pair length scale. When DNA is confined to a …

The human genome contains multiple layers of information that extend beyond the genetic
sequence. In fact, identical genetics do not necessarily yield identical phenotypes as evident …

Carbapenem-resistant Enterobacterales (CRE) is an increasing problem worldwide. Here,
we examined the clonal relatedness of 71 non-repetitive CRE isolates collected in a …

Nucleic acids are important biomarkers for disease detection, monitoring, and treatment.
Advances in technologies for nucleic acid analysis have enabled discovery and clinical …