Traumatic brain injury: a disease process, not an event

BE Masel, DS DeWitt - Journal of neurotrauma, 2010 - liebertpub.com
Traumatic brain injury (TBI) is seen by the insurance industry and many health care
providers as an “event.” Once treated and provided with a brief period of rehabilitation, the …

Infections after a traumatic brain injury: The complex interplay between the immune and neurological systems

R Sharma, SR Shultz, MJ Robinson, A Belli… - Brain, behavior, and …, 2019 - Elsevier
Traumatic brain injury (TBI) is a serious global health issue, being the leading cause of
death and disability for individuals under the age of 45, and one of the largest causes of …

Management of penetrating brain injury

SF Kazim, MS Shamim, MZ Tahir… - … , Trauma, and Shock, 2011 - journals.lww.com
Penetrating brain injury (PBI), though less prevalent than closed head trauma, carries a
worse prognosis. The publication of Guidelines for the Management of Penetrating Brain …

Mapping connectivity damage in the case of Phineas Gage

JD Van Horn, A Irimia, CM Torgerson, MC Chambers… - PloS one, 2012 - journals.plos.org
White matter (WM) mapping of the human brain using neuroimaging techniques has gained
considerable interest in the neuroscience community. Using diffusion weighted (DWI) and …

Correlates of posttraumatic epilepsy 35 years following combat brain injury

V Raymont, AM Salazar, R Lipsky, D Goldman… - Neurology, 2010 - AAN Enterprises
Background: The Vietnam Head Injury Study (VHIS) is a prospective, longitudinal follow-up
of 1,221 Vietnam War veterans with mostly penetrating head injuries (PHIs). The high …

Hypoxia‐inducible factor 1 alpha (HIF‐1α) stimulated and P2X7 receptor activated by COVID-19, as a potential therapeutic target and risk factor for epilepsy

H Zalpoor, A Akbari, M Nabi-Afjadi… - Human Cell, 2022 - Springer
Based on available evidence, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) is a neuroinvasive virus. According to the centers for disease control and prevention …

Outcomes following penetrating brain injuries in military settings: a systematic review and meta-analysis

CL Karras, P Texakalidis, JZ Nie, HM Tran… - World neurosurgery, 2022 - Elsevier
Objective While neurosurgeons are experienced in treating penetrating brain injuries (PBIs)
in civilian settings, much less is known about management and outcomes of PBIs in military …

Insights into epileptogenesis from post-traumatic epilepsy

M Pease, K Gupta, SL Moshé, DJ Correa… - Nature Reviews …, 2024 - nature.com
Post-traumatic epilepsy (PTE) accounts for 5% of all epilepsies. The incidence of PTE after
traumatic brain injury (TBI) depends on the severity of injury, approaching one in three in …

Association of the severity of cortical damage with the occurrence of spontaneous seizures and hyperexcitability in an animal model of posttraumatic epilepsy

I Kharatishvili, A Pitkänen - Epilepsy research, 2010 - Elsevier
Posttraumatic epilepsy is a common consequence of traumatic brain injury in humans. Major
predictors for the development of posttraumatic epilepsy include the severity of injury and …

Surgical management of civilian gunshot wounds to the head

B Aarabi, C Mossop, JA Aarabi - Handbook of clinical neurology, 2015 - Elsevier
Each year close to 20 000 Americans are involved in gunshot wounds to the head (GSWH).
Over 90% of the victims of GSWH eventually fail to survive and only a meager 5% of the …