[PDF][PDF] The effectiveness of green tea or green tea extract on insulin resistance and glycemic control in type 2 diabetes mellitus: a meta-analysis

J Yu, P Song, R Perry, C Penfold… - … & Metabolism Journal, 2017 - synapse.koreamed.org
Green tea or green tea extract (GT/GTE) has been demonstrated to reduce insulin resistance
and improve glycemic control. However, evidence for this health beneficial effect is …

Translating the genetics of cystic fibrosis to personalized medicine

H Corvol, KE Thompson, O Tabary, P Le Rouzic… - Translational …, 2016 - Elsevier
Cystic fibrosis (CF) is the most common life-threatening recessive genetic disease in the
Caucasian population. This multiorgan disease is caused by mutations in the gene …

Machine learning and network analyses reveal disease subtypes of pancreatic cancer and their molecular characteristics

M Sinkala, N Mulder, D Martin - Scientific reports, 2020 - nature.com
Given that the biological processes governing the oncogenesis of pancreatic cancers could
present useful therapeutic targets, there is a pressing need to molecularly distinguish …

A visual and curatorial approach to clinical variant prioritization and disease gene discovery in genome-wide diagnostics

RA James, IM Campbell, ES Chen, PM Boone… - Genome medicine, 2016 - Springer
Background Genome-wide data are increasingly important in the clinical evaluation of
human disease. However, the large number of variants observed in individual patients …

High ELF4 expression in human cancers is associated with worse disease outcomes and increased resistance to anticancer drugs

D Kafita, V Daka, P Nkhoma, M Zulu, E Zulu, R Tembo… - PloS one, 2021 - journals.plos.org
The malignant phenotype of tumour cells is fuelled by changes in the expression of various
transcription factors, including some of the well-studied proteins such as p53 and Myc …

Precision nutrition in chronic inflammation

TJ Demetrowitsch, K Schlicht, C Knappe… - Frontiers in …, 2020 - frontiersin.org
The molecular foundation of chronic inflammatory diseases (CIDs) can differ markedly
between individuals. As our understanding of the biochemical mechanisms underlying …

Comprehensive multi-omics profiling identifies novel molecular subtypes of pancreatic ductal adenocarcinoma

X Wang, J Yang, B Ren, G Yang, X Liu, R Xiao, J Ren… - Genes & …, 2023 - Elsevier
Pancreatic cancer, a highly fatal malignancy, is predicted to rank as the second leading
cause of cancer-related death in the next decade. This highlights the urgent need for new …

Complex interventions deserve complex evaluations: a transdisciplinary approach to evaluation of a preventive personalized medicine intervention

EM Garton, S Savaş, C Pell, EV Syurina… - Frontiers in public …, 2022 - frontiersin.org
Non-communicable diseases (NCDs) are the largest cause of disability and death globally.
The human and financial costs of NCDs have raised questions of sustainability for many …

Higher vegetable protein consumption, assessed by an isoenergetic macronutrient exchange model, is associated with a lower presence of overweight and obesity in …

S Navas-Carretero, R San-Cristobal… - … Journal of Food …, 2019 - Taylor & Francis
The objective was to evaluate differences in macronutrient intake and to investigate the
possible association between consumption of vegetable protein and the risk of …

How complex is the microarray dataset? A novel data complexity metric for biological high-dimensional microarray data

Z Sha, L Zhu, Z Jiang, Y Chen, T Hu - arXiv preprint arXiv:2308.06430, 2023 - arxiv.org
Data complexity analysis quantifies the hardness of constructing a predictive model on a
given dataset. However, the effectiveness of existing data complexity measures can be …