T cell receptors (TCRs) are protein complexes formed by six different polypeptides. In most T
cells, TCRs are composed of αβ subunits displaying immunoglobulin-like variable domains …

The number of possible T cell activation outcomes resulting from T cell receptor (TCR)
engagement suggests that the TCR is able to differentially activate a myriad of signaling …

The CD3 complex found associated with the T cell receptor (TCR) is essential for signal
transduction following TCR engagement. During T cell development, TCR‐mediated …

Several studies have addressed the question of starvation effects on immune function by
means of changes in lymphocyte subsets, cytokine induction or lymphocyte activation …

CD3γ and CD3δ are the most closely related CD3 components, both of which participate in
the TCRαβ–CD3 complex expressed on mature T cells. Interestingly, however, CD3δ does …

The T–cell receptor (TCR) is composed of two glycoproteins (α and β or γ and δ) associated
with four invariant polypeptides (CD3–γ, δ, ε and ζ). The majority of TCR/CD3 complexes …

Transfected T cell receptor (TCR) beta chain genes are expressed as homodimers on the
surface of immature (Sci/ET27F) but not on mature (58 alpha‐beta‐) T cell lines which lack …

The TCR/CD3 complex is composed of six subunits which are expressed on the cell surface
in a coordinate fashion after assembly in the endoplasmic reticulum (ER). The TCR/CD3 …

CD3ζ is a subunit of the T-cell antigen receptor (TCR) complex required for its assembly and
surface expression that also plays an important role in TCR-mediated signal transduction …

The T-cell antigen receptor (αβ or γδ TCR) is known to associate with four polypeptides
(CD3 γ, δ, ϵ and ζ) to form the TCR-CD3 complex. Although the six chains are well …