[HTML][HTML] Approaches for corneal endothelium regenerative medicine
The state of the art therapy for treating corneal endothelial disease is transplantation.
Advances in the reproducibility and accessibility of surgical techniques are increasing the …
Advances in the reproducibility and accessibility of surgical techniques are increasing the …
Animal models in eye research: focus on corneal pathologies
A Loiseau, G Raîche-Marcoux, C Maranda… - International Journal of …, 2023 - mdpi.com
The eye is a complex sensory organ that enables visual perception of the world. The
dysfunction of any of these tissues can impair vision. Conduction studies on laboratory …
dysfunction of any of these tissues can impair vision. Conduction studies on laboratory …
An effective method for culturing functional human corneal endothelial cells using a xenogeneic free culture medium
S Alonso-Alonso, N Vázquez, M Chacón… - Scientific reports, 2023 - nature.com
Endothelial dysfunction is a leading cause of corneal blindness in developed countries and
the only available treatment is the endothelial transplantation. However, the limited …
the only available treatment is the endothelial transplantation. However, the limited …
[HTML][HTML] Animal models of corneal endothelial dysfunction to facilitate development of novel therapies
Progressive corneal endothelial disease eventually leads to corneal edema and vision loss
due to the limited regenerative capacity of the corneal endothelium in vivo and is a major …
due to the limited regenerative capacity of the corneal endothelium in vivo and is a major …
Early and late-onset cell migration from peripheral corneal endothelium
A Miron, S Ní Dhubhghaill, V Kocaba, MJ Jager… - PLoS …, 2023 - journals.plos.org
In this study we describe peripheral corneal endothelial cell migration in vitro in the absence
and presence of a ROCK-inhibitor. For this study, 21 corneal endothelial graft rims, with …
and presence of a ROCK-inhibitor. For this study, 21 corneal endothelial graft rims, with …
Temperature Dependence of Membrane Permeability Parameters for Five Cell Types Using Nonideal Thermodynamic Assumptions to Mathematically Model …
F Yadegari, LA Gabler Pizarro… - The Journal of …, 2024 - ACS Publications
Cryopreservation is the process of preserving biological matter at subzero temperatures for
long-term storage. During cryopreservation, cells are susceptible to various injuries that can …
long-term storage. During cryopreservation, cells are susceptible to various injuries that can …
[HTML][HTML] Towards Clinical Application: Calcium Waves for In Vitro Qualitative Assessment of Propagated Primary Human Corneal Endothelial Cells
XY Ng, G Peh, F Morales-Wong, R Gabriel, PL Soong… - Cells, 2024 - mdpi.com
Corneal endothelium cells (CECs) regulate corneal hydration between the leaky barrier of
the corneal endothelium and the ionic pumps on the surface of CECs. As CECs do not …
the corneal endothelium and the ionic pumps on the surface of CECs. As CECs do not …
Beneficial effects of polydeoxyribonucleotide (PDRN) in an in vitro model of fuchs endothelial corneal dystrophy
I Ceravolo, F Mannino, N Irrera, L Minutoli, V Arcoraci… - Pharmaceuticals, 2022 - mdpi.com
Fuchs endothelial corneal dystrophy (FECD) is a bilateral, hereditary syndrome
characterized by progressive irreversible injury in the corneal endothelium; it is the most …
characterized by progressive irreversible injury in the corneal endothelium; it is the most …
Long-term observation after transplantation of cultured human corneal endothelial cells for corneal endothelial dysfunction
P Sun, L Shen, YB Li, LQ Du, XY Wu - Stem Cell Research & Therapy, 2022 - Springer
Background Corneal transplantation is the only way to treat serious corneal diseases
caused by corneal endothelial dysfunction. However, the shortage of donor corneal tissues …
caused by corneal endothelial dysfunction. However, the shortage of donor corneal tissues …
Medizinische Ansätze zur Regeneration des Hornhautendothels
P Català, G Thuret, H Skottman, JS Mehta… - Kompass …, 2023 - karger.com
Zusammenfassung Die modernste Therapie zur Behandlung von
Hornhautendothelerkrankungen ist die Transplantation. Fortschritte in der …
Hornhautendothelerkrankungen ist die Transplantation. Fortschritte in der …