Cyclodextrin-membrane interaction in drug delivery and membrane structure maintenance
Z Hammoud, N Khreich, L Auezova… - International journal of …, 2019 - Elsevier
Cyclodextrins (CDs) are cyclic oligosaccharides able to improve drug water solubility and
stability by forming CD/drug inclusion complexes. To further increase drug entrapment and …
stability by forming CD/drug inclusion complexes. To further increase drug entrapment and …
Grading the commercial optical biosensor literature—Class of 2008:'The Mighty Binders'
RL Rich, DG Myszka - Journal of Molecular Recognition: An …, 2010 - Wiley Online Library
Optical biosensor technology continues to be the method of choice for label‐free, real‐time
interaction analysis. But when it comes to improving the quality of the biosensor literature …
interaction analysis. But when it comes to improving the quality of the biosensor literature …
Molecular mechanism of cyclodextrin mediated cholesterol extraction
CA López, AH de Vries, SJ Marrink - PLoS computational biology, 2011 - journals.plos.org
The depletion of cholesterol from membranes, mediated by β-cyclodextrin (β-CD) is well
known and documented, but the molecular details of this process are largely unknown …
known and documented, but the molecular details of this process are largely unknown …
A mitochondrial NADPH-cholesterol axis regulates extracellular vesicle biogenesis to support hematopoietic stem cell fate
Mitochondrial fatty acid oxidation (FAO) is essential for hematopoietic stem cell (HSC) self-
renewal; however, the mechanism by which mitochondrial metabolism controls HSC fate …
renewal; however, the mechanism by which mitochondrial metabolism controls HSC fate …
Efficacy and ototoxicity of different cyclodextrins in Niemann–Pick C disease
CD Davidson, YI Fishman, I Puskás… - Annals of Clinical …, 2016 - Wiley Online Library
Abstract Objective Niemann–Pick type C (NPC) disease is a fatal, neurodegenerative,
lysosomal storage disorder characterized by intracellular accumulation of unesterified …
lysosomal storage disorder characterized by intracellular accumulation of unesterified …
Cyclodextrin polymer improves atherosclerosis therapy and reduces ototoxicity
H Kim, J Han, JH Park - Journal of Controlled Release, 2020 - Elsevier
Recently, cyclodextrin (CD) has shown the potential for effective treatment of atherosclerotic
plaques in mice by solubilizing plaque cholesterol. While promising as a new therapy for …
plaques in mice by solubilizing plaque cholesterol. While promising as a new therapy for …
Drug-in-cyclodextrin-in-liposomes: A promising delivery system for hydrophobic drugs
Introduction: Recently, the entrapment of hydrophobic drugs in the form of water-soluble
drug–cyclodextrin (CD) complex in liposomes has been investigated as a new strategy to …
drug–cyclodextrin (CD) complex in liposomes has been investigated as a new strategy to …
An impedance-based approach for sensing cyclodextrin-mediated modulation of membrane cholesterol
Cyclodextrin molecules are increasingly being used in biological research and as
therapeutic agents to alter membrane cholesterol content, yet there is much to learn about …
therapeutic agents to alter membrane cholesterol content, yet there is much to learn about …
Active membrane cholesterol as a physiological effector
Y Lange, TL Steck - Chemistry and physics of lipids, 2016 - Elsevier
Sterols associate preferentially with plasma membrane sphingolipids and saturated
phospholipids to form stoichiometric complexes. Cholesterol in molar excess of the capacity …
phospholipids to form stoichiometric complexes. Cholesterol in molar excess of the capacity …
[HTML][HTML] Interactions between cyclodextrins and cellular components: Towards greener medical applications?
L Leclercq - Beilstein journal of organic chemistry, 2016 - beilstein-journals.org
In the field of host–guest chemistry, some of the most widely used hosts are probably
cyclodextrins (CDs). As CDs are able to increase the water solubility of numerous drugs by …
cyclodextrins (CDs). As CDs are able to increase the water solubility of numerous drugs by …