Comprehensive metabolite profiling of Berdav propolis using LC-MS/MS: Determination of antioxidant, anticholinergic, antiglaucoma, and antidiabetic effects

H Karagecili, MA Yılmaz, A Ertürk, H Kiziltas, L Güven… - Molecules, 2023 - mdpi.com
Propolis is a complex natural compound that honeybees obtain from plants and contributes
to hive safety. It is rich in phenolic and flavonoid compounds, which contain antioxidant …

Comprehensive Metabolite Profiling of Cinnamon (Cinnamomum zeylanicum) Leaf Oil Using LC-HR/MS, GC/MS, and GC-FID: Determination of Antiglaucoma …

M Mutlu, Z Bingol, EM Uc, E Köksal, AC Goren… - Life, 2023 - mdpi.com
In this study, for the first time, the antioxidant and antidiabetic properties of the essential oil
from cinnamon (Cinnamomum zeylanicum) leaves were evaluated and investigated using …

Antioxidant, antidiabetic, anticholinergic, and antiglaucoma effects of magnofluorine

L Durmaz, H Kiziltas, L Guven, H Karagecili, S Alwasel… - Molecules, 2022 - mdpi.com
Magnofluorine, a secondary metabolite commonly found in various plants, has
pharmacological potential; however, its antioxidant and enzyme inhibition effects have not …

Recent advances in the natural product analogues for the treatment of neurodegenerative diseases

J Zhang, P Jiang, S Wang, M Li, Z Hao, W Guan… - Bioorganic …, 2024 - Elsevier
Neurodegenerative diseases (NDs) represent a hallmark of numerous incapacitating and
untreatable conditions, the incidence of which is escalating swiftly, exemplified by …

[PDF][PDF] Analysis of phenolic compounds by LC-HRMS and determination of antioxidant and enzyme inhibitory properties of verbascum speciousum schrad

H Kızıltaş, Z Bingöl, AC Gören, SH Alwasel, İ Gülçin - Rec. Nat. Prod, 2023 - acgpubs.org
Studies have shown an inverse correlation between age-related illnesses like coronary
heart disease and cancer and fruit and vegetable intake. Given the probable health benefits …

Metal‐Free Synthesis via Intramolecular Cyclization, Enzyme Inhibition Properties and Molecular Docking of Novel Isoindolinones

U Atmaca, R Saglamtas, Y Sert, M Çelik… - …, 2023 - Wiley Online Library
Highly effective one‐pot synthesis of novel isoindolinones from various 2‐benzoylbenzoic
acid derivatives with intramolecular cyclization in the presence of chlorosulfonyl isocyanate …

The palladium-based complexes bearing 1, 3-dibenzylbenzimidazolium with morpholine, triphenylphosphine, and pyridine derivate ligands: Synthesis …

A Aktaş, G Yakalı, Y Demir, İ Gülçin, M Aygün, Y Gök - Heliyon, 2022 - cell.com
The palladium-based complexes bearing N-heterocyclic carbene (NHC) ligand have long
attracted attention as active catalysts for many catalytic reactions. Recently, the biological …

Structure-based inhibition of acetylcholinesterase and butyrylcholinesterase with 2-Aryl-6-carboxamide benzoxazole derivatives: synthesis, enzymatic assay, and in …

B Kuzu, MA Alagoz, Y Demir, I Gulcin, S Burmaoglu… - Molecular Diversity, 2024 - Springer
An important research topic is the discovery of multifunctional compounds targeting different
disease-causing components. This research aimed to design and synthesize a series of 2 …

Naringenin, Hesperidin and Quercetin Ameliorate Radiation‐Induced Damage In Rats: In Vivo And In Silico Evaluations

H Uguz, B Avcı, E Palabıyık… - Chemistry & …, 2024 - Wiley Online Library
In this study, we sought to determine how well naringenin, hesperidin, and quercetin
prevented damage brought on by radiotherapy. During the investigation, 48 adult female …

Substituted bisbenzimidazole derivatives as multiple targeting agents to treat Alzheimer's disease, diabetes, and microbial infections

O Algul, B Mete, B Turkmenoglu, R Saglamtas… - Journal of Molecular …, 2025 - Elsevier
This study presents the synthesis and bioactivity screening of a series of substituted
bisbenzimidazoles (3a–l), assessed for their inhibitory effects on α-glycosidase, α-amylase …