A wide array of molecular pathways has been investigated during the past decade in order
to understand the mechanisms by which the practice of physical exercise promotes …

Dementia is one of the greatest global challenges for health and social care in the 21st
century. Alzheimer's disease (AD), the most common type of dementia, is by no means an …

Alzheimer's disease (AD) is a chronic neurodegenerative disease, with the characteristics of
neurofibrillary tangle (NFT) and senile plaque (SP) formation. Although great progresses …

Recent years have witnessed a revolution in our understanding of microglia biology,
including their major role in the etiology and pathogenesis of neurodegenerative diseases …

Physical activity plays an essential role in maintaining a healthy body, yet it also provides
unique benefits for the vascular and cellular systems that sustain a healthy brain. While the …

Due to a sedentary lifestyle, more and more people are becoming obese nowadays. In
addition to health‐related problems, obesity can also impair cognition and motor …

Physical exercise may improve cognitive function by modulating molecular and cellular
mechanisms within the brain. We propose that the facilitation of long-term synaptic …

Background Despite widespread acceptance that neuroinflammation contributes to age-
related cognitive decline, studies comparing protein expression of cytokines in the young …

Background Both human and animal studies have shown beneficial effects of physical
exercise on brain health but most tend to be based on aerobic rather than resistance type …

Growing evidence has shown the beneficial influence of exercise on humans. Apart from
classic cardioprotection, numerous studies have demonstrated that different exercise …