Abstract Coronavirus Disease 2019 (COVID-19) has been the most severe public health
challenge in this century. Two years after its emergence, the rapid development and …

Abstract mRNA vaccines have won the race for early COVID-19 vaccine approval, yet
improvements are necessary to retain this leading role in combating infectious diseases. A …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of
concern comprises several sublineages, with BA. 2 and BA. 2.12. 1 having replaced the …

SARS-CoV-2 Omicron is highly transmissible and has substantial resistance to
neutralization following immunization with ancestral spike-matched vaccines. It is unclear …

The Omicron variant of SARS-CoV-2 recently swept the globe and showed high level of
immune evasion. Here, we generate an Omicron-specific lipid nanoparticle (LNP) mRNA …

Abstract ChAdOx1 nCoV-19 (AZD1222) is a replication-deficient simian adenovirus–
vectored vaccine encoding the spike (S) protein of SARS-CoV-2, based on the first …

RNA vaccines possess significant clinical promise in counteracting human diseases caused
by infectious or cancerous threats. Self-amplifying replicon RNA (repRNA) has been thought …

Summary The SARS-CoV-2 Omicron variant escapes neutralizing antibodies elicited by
vaccines or infection. However, whether Omicron triggers cross-reactive humoral responses …

Summary Background Crimean-Congo hemorrhagic fever virus is the cause of a severe
hemorrhagic fever with cases reported throughout a wide-geographic region. Spread by the …

Next-generation COVID-19 vaccines are critical due to the ongoing evolution of SARS-CoV-
2 virus and rapid waning duration of the neutralizing antibody response against current …