The immune-inflammatory response is associated with increased nitro-oxidative stress. The
aim of this mechanistic review is to examine:(a) the role of redox-sensitive transcription …

Thrombosis is the most feared complication of cardiovascular diseases and a main cause of
death worldwide, making it a major health-care challenge. Platelets and the coagulation …

Background: Severe acute respiratory syndrome corona virus 2 infection causes severe
pneumonia (coronavirus disease 2019 [COVID-19]), but the mechanisms of subsequent …

The full neutrophil heterogeneity and differentiation landscape remains incompletely
characterized. Here, we profiled> 25,000 differentiating and mature mouse neutrophils using …

Classically considered short-lived and purely defensive leukocytes, neutrophils are unique
in their fast and moldable response to stimulation. This plastic behavior may underlie …

Neutrophils are the most abundant circulating leukocytes, being the first line of defence
against bacterial and fungal infections. However, neutrophils also contribute to tissue …

Sepsis is a deadly inflammatory syndrome caused by an exaggerated immune response to
infection. Much has been focused on host response to pathogens mediated through the …

Osteosarcoma, with poor survival after metastasis, is considered the most common primary
bone cancer in adolescents. Notwithstanding the efforts of researchers, its five-year survival …

Neutrophils are frontline cells of the innate immune system. These effector leukocytes are
equipped with intriguing antimicrobial machinery and consequently display high cytotoxic …

Neutrophils are the most abundant leukocytes in the circulation, and have been regarded as
first line of defense in the innate arm of the immune system. They capture and destroy …