Age-associated chronic inflammation is characterized by unresolved and uncontrolled
inflammation with multivariable low-grade, chronic and systemic responses that exacerbate …

During aging, body adiposity increases with changes in the metabolism of lipids and their
metabolite levels. Considering lipid metabolism, excess adiposity with increased lipotoxicity …

Vascular smooth muscle cells (VSMCs) are an important source of foam cells in
atherosclerosis. The mechanism for VSMC-derived foam cell formation is, however, poorly …

Background Acute kidney injury (AKI) is often secondary to sepsis. Previous studies suggest
that damaged mitochondria and the inhibition of autophagy results in AKI during sepsis, but …

Background Cognitive deficits are common in patients with sepsis. Previous studies in
sepsis-associated encephalopathy (SAE) implicated the CXC chemokine receptor type …

Autophagy is an important housekeeping process that maintains a proper cellular
homeostasis under normal physiologic and/or pathologic conditions. It is responsible for the …

Thymol is a natural antibacterial agent found in the essential oil extracted from thyme, which
has been proven to be beneficial in food and medicine. Meanwhile, the NOD-like receptor …

Inflammation and autophagy occur during hepatic fibrosis development caused by various
pathogens, and effectively curbing of autophage may delay the occurrence of hepatic …

Cannabidiol (CBD) is a terpenoid naturally found in plants. The purified compound is used
in the treatment of mental disorders because of its antidepressive, anxiolytic, and …

A better understanding of the molecular mechanism of intestinal fatty acid absorption could
lead to novel approaches to treatment and prevention of fatty acid–related metabolic …