[HTML][HTML] Statistics and network-based approaches to identify molecular mechanisms that drive the progression of breast cancer

MS Alam, MM Rahaman, A Sultana, G Wang… - Computers in Biology …, 2022 - Elsevier
Breast cancer (BC) is one of the most malignant tumors and the leading cause of cancer-
related death in women worldwide. So, an in-depth investigation on the molecular …

Splicing dysregulation as a driver of breast cancer

A Read, R Natrajan - Endocrine-related cancer, 2018 - erc.bioscientifica.com
Breast cancer is known to be a heterogeneous disease driven by a large repertoire of
molecular abnormalities, which contribute to its diverse clinical behaviour. Despite the …

RFC3 serves as a novel prognostic biomarker and target for head and neck squamous cell carcinoma

KR Avs, C Pandi, B Kannan, A Pandi… - Clinical Oral …, 2023 - Springer
Objective Head and neck squamous cell carcinoma (HNSCC) is a prevalent cancer that
originates from the squamous cells. The role of the replication factor C subunit 3 (RFC3) in …

[HTML][HTML] RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis

CE Bond, DM McKeone, M Kalimutho, ML Bettington… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Serrated pathway colorectal cancers (CRCs) are characterised by a BRAF mutation and half
display microsatellite instability (MSI). The Wnt pathway is commonly upregulated in …

Aberrations of chromosomes 1 and 16 in breast cancer: a framework for cooperation of transcriptionally dysregulated genes

AP Privitera, V Barresi, DF Condorelli - Cancers, 2021 - mdpi.com
Simple Summary Classical cytogenetic studies in breast cancer have identified frequent
chromosomal aberrations that produce an increased gene copy number in chromosome 1q …

Sequential gene expression analysis of cervical malignant transformation identifies RFC4 as a novel diagnostic and prognostic biomarker

J Zhang, S Meng, X Wang, J Wang, X Fan, H Sun… - BMC medicine, 2022 - Springer
Background Cervical squamous cell carcinoma (SCC) is known to arise through
increasingly higher-grade squamous intraepithelial lesions (SILs) or cervical intraepithelial …

[HTML][HTML] RFC3 induces epithelial‑mesenchymal transition in lung adenocarcinoma cells through the Wnt/β‑catenin pathway and possesses prognostic value in lung …

S Gong, X Qu, S Yang, S Zhou… - International …, 2019 - spandidos-publications.com
Lung cancer is a malignant tumor responsible for the highest mortality rate in humans. The
identification of novel functional genes is of great importance in the treatment of lung cancer …

Systematic identification of key genes and pathways in the development of invasive cervical cancer

G Niu, D Wang, Y Pei, L Sun - Gene, 2017 - Elsevier
Background Cervical cancer progresses through different stages: a long stage of
precancerous lesions, then high-grade squamous intraepithelial lesion (HSIL) stage in …

An ensemble predictive modeling framework for breast cancer classification

R Nagarajan, M Upreti - Methods, 2017 - Elsevier
Molecular changes often precede clinical presentation of diseases and can be useful
surrogates with potential to assist in informed clinical decision making. Recent studies have …

Enhanced dependency of KRAS‐mutant colorectal cancer cells on RAD 51‐dependent homologous recombination repair identified from genetic interactions in …

M Kalimutho, AL Bain, B Mukherjee, P Nag… - Molecular …, 2017 - Wiley Online Library
Activating KRAS mutations drive colorectal cancer tumorigenesis and influence response to
anti‐EGFR‐targeted therapy. Despite recent advances in understanding Ras signaling …