Mechanisms of sex differences in Alzheimer's disease

C Lopez-Lee, ERS Torres, G Carling, L Gan - Neuron, 2024 - cell.com
Alzheimer's disease (AD) and the mechanisms underlying its etiology and progression are
complex and multifactorial. The higher AD risk in women may serve as a clue to better …

[HTML][HTML] Sex and gender in health research: Intersectionality matters

S Subramaniapillai, LAM Galea, G Einstein… - Frontiers in …, 2023 - Elsevier
Research policies aiming to integrate sex and gender in scientific studies are receiving
increased attention in academia. Incorporating these policies into health research is …

Augmented reality versus standard tests to assess cognition and function in early Alzheimer's disease

M Muurling, C de Boer, S Vairavan, RL Harms… - NPJ digital …, 2023 - nature.com
Augmented reality (AR) apps, in which the virtual and real world are combined, can recreate
instrumental activities of daily living (IADL) and are therefore promising to measure cognition …

Gender and age influence the association between gait speed and mild cognitive impairment in community‐dwelling Japanese older adults: from the Japan …

S Bun, K Suzuki, H Niimura, R Shikimoto… - …, 2023 - Wiley Online Library
Background Studies have shown that decreased gait speed is associated with impaired
cognitive function. However, whether this association is equivalent across ages or genders …

Neglecting sex and gender in research is a public-health risk

S Haupt, C Carcel, R Norton - Nature, 2024 - nature.com
Neglecting sex and gender in research is a public-health risk Skip to main content Thank you
for visiting nature.com. You are using a browser version with limited support for CSS. To obtain …

Low-Dose Radiation Therapy Impacts Microglial Inflammatory Response without Modulating Amyloid Load in Female TgF344-AD Rats

K Ceyzériat, E Jaques, Y Gloria… - Journal of …, 2024 - content.iospress.com
Background: Low-dose radiation therapy (LD-RT) has demonstrated in preclinical and
clinical studies interesting properties in the perspective of targeting Alzheimer's disease …

Sex and age differences in geriatric pharmacotherapy

S Hilmer, P Rochon - Public Policy & Aging Report, 2023 - academic.oup.com
Older men and women are major users of therapeutic drugs. Indeed, modern medicine,
including use of therapeutic drugs, has made a major contribution to the aging of our …

Cardiometabolic health across menopausal years is linked to white matter hyperintensities up to a decade later

LS Schindler, S Subramaniapillai… - Frontiers in global …, 2023 - frontiersin.org
Introduction The menopause transition is associated with several cardiometabolic risk
factors. Poor cardiometabolic health is further linked to microvascular brain lesions, which …

Considering challenges for the new Alzheimer's drugs: Clinical, population, and health system perspectives

S Walsh, R Merrick, R Milne, S Nurock… - Alzheimer's & …, 2024 - Wiley Online Library
Recent approvals of amyloid immunotherapy drugs for early Alzheimer's disease (AD) have
been highly controversial. In this piece, we consider challenges from the clinical, population …

Sex-and dose-dependent catalase increase and its clinical impact in a benzoate dose-finding, randomized, double-blind, placebo-controlled trial for Alzheimer's …

HY Lane, SH Wang, CH Lin - Pharmacology Biochemistry and Behavior, 2024 - Elsevier
Abstract Background Sex differences in Alzheimer's disease (AD) are gaining increasing
attention. Previously research has shown that sodium benzoate treatment can improve …