The most widespread intracellular bacteria in the animal kingdom are maternally inherited
endosymbionts of the genus Wolbachia. Their prevalence in arthropods and nematodes …

Dengue, caused by infection of any of four dengue virus serotypes (DENV-1 to DENV-4), is a
mosquito-borne disease of major public health concern associated with significant morbidity …

Background Aedes aegypti mosquitoes infected with the w Mel strain of Wolbachia pipientis
are less susceptible than wild-type A. aegypti to dengue virus infection. Methods We …

The range of the mosquito Aedes aegypti continues to expand, putting more than two billion
people at risk of arboviral infection. The sterile insect technique (SIT) has been used to …

Background: The wMel strain of Wolbachia has been successfully introduced into Aedes
aegypti mosquitoes and subsequently shown in laboratory studies to reduce transmission of …

The COVID-19 pandemic galvanized the field of virus genomic surveillance, demonstrating
its utility for public health. Now, we must harness the momentum that led to increased …

Background Mosquito-borne viruses—such as Zika, chikungunya, dengue fever, and yellow
fever, among others—are of global importance. Although vaccine development for …

Background: A number of new technologies are under development for the control of
mosquito transmitted viruses, such as dengue, chikungunya and Zika that all require the …

Dengue viruses have spread rapidly within countries and across regions in the past few
decades, resulting in an increased frequency of epidemics and severe dengue disease …

Dengue has enormous health impacts globally. A novel approach to decrease dengue
incidence involves the introduction of Wolbachia endosymbionts that block dengue virus …