Within-host nucleotide diversity of virus populations: insights from next-generation sequencing
CW Nelson, AL Hughes - Infection, Genetics and Evolution, 2015 - Elsevier
Next-generation sequencing (NGS) technology offers new opportunities for understanding
the evolution and dynamics of viral populations within individual hosts over the course of …
the evolution and dynamics of viral populations within individual hosts over the course of …
Simultaneous detection of hepatitis C virus and interferon stimulated gene expression in infected human liver
S Wieland, Z Makowska, B Campana… - …, 2014 - Wiley Online Library
Approximately 50% of patients with chronic hepatitis C (CHC) have ongoing expression of
interferon stimulated genes (ISGs) in the liver. It is unclear why this endogenous antiviral …
interferon stimulated genes (ISGs) in the liver. It is unclear why this endogenous antiviral …
BK polyomavirus diversity—why viral variation matters
JT Blackard, SM Davies… - Reviews in medical …, 2020 - Wiley Online Library
BK polyomavirus (BKPyV or BKV) is a non‐enveloped, circular double‐stranded DNA virus
that may exceed 80% seroprevalence in adults. BKV infection typically occurs during …
that may exceed 80% seroprevalence in adults. BKV infection typically occurs during …
Genome-wide hepatitis C virus amino acid covariance networks can predict response to antiviral therapy in humans
Hepatitis C virus (HCV) is a common RNA virus that causes hepatitis and liver cancer.
Infection is treated with IFN-α and ribavirin, but this expensive and physically demanding …
Infection is treated with IFN-α and ribavirin, but this expensive and physically demanding …
Evidence for separation of HCV subtype 1a into two distinct clades
The nucleotide sequence diversity present among hepatitis C virus (HCV) isolates allows
rapid adjustment to exterior forces including host immunity and drug therapy. This viral …
rapid adjustment to exterior forces including host immunity and drug therapy. This viral …
HCV genetic variability: from quasispecies evolution to genotype classification
C Argentini, D Genovese, S Dettori… - Future …, 2009 - Taylor & Francis
HCV is a ssRNA virus belonging to the Flaviviruses and is found worldwide worldwide in
humans. Following primary infection, persistent infection develops in more than 85% of …
humans. Following primary infection, persistent infection develops in more than 85% of …
Prediction of hepatitis C virus interferon/ribavirin therapy outcome based on viral nucleotide attributes using machine learning algorithms
Abstract Background Hepatitis C virus (HCV) causes chronic hepatitis C in 2-3% of world
population and remains one of the health threatening human viruses, worldwide. In the …
population and remains one of the health threatening human viruses, worldwide. In the …
Hepatitis-C virus and cirrhosis: an overview from Khyber Pakhtunkhwa province of Pakistan
Hepatitis C virus (HCV) leads to liver cirrhosis and carcinoma worldwide. The data of HCV
cirrhotic patients were collected from hospitals of Peshawar in the period from 2015 to 2018 …
cirrhotic patients were collected from hospitals of Peshawar in the period from 2015 to 2018 …
Use of illumina deep sequencing technology to differentiate hepatitis C virus variants
M Ninomiya, Y Ueno, R Funayama… - Journal of clinical …, 2012 - Am Soc Microbiol
Hepatitis C virus (HCV) is a positive-strand enveloped RNA virus that shows diverse viral
populations even in one individual. Though Sanger sequencing has been used to determine …
populations even in one individual. Though Sanger sequencing has been used to determine …
Comparison of the mechanisms of drug resistance among HIV, hepatitis B, and hepatitis C
S Margeridon-Thermet, RW Shafer - Viruses, 2010 - mdpi.com
Human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV)
are the most prevalent deadly chronic viral diseases. HIV is treated by small molecule …
are the most prevalent deadly chronic viral diseases. HIV is treated by small molecule …