Splittable systems in biomedical applications

S Yuan, A Bremmer, X Yang, J Li, Q Hu - Biomaterials Science, 2024 - pubs.rsc.org
Splittable systems have emerged as a powerful approach for the precise spatiotemporal
control of biological processes. This concept relies on splitting a functional molecule into …

Charting cellular differentiation trajectories with Ricci flow

A Baptista, BD MacArthur, CRS Banerji - Nature Communications, 2024 - nature.com
Complex biological processes, such as cellular differentiation, require intricate rewiring of
intra-cellular signalling networks. Previous characterisations revealed a raised network …

A unified approach of detecting phase transition in time-varying complex networks

MR Znaidi, J Sia, S Ronquist, I Rajapakse… - Scientific reports, 2023 - nature.com
Deciphering the non-trivial interactions and mechanisms driving the evolution of time-
varying complex networks (TVCNs) plays a crucial role in designing optimal control …

Augmentations of Forman's Ricci curvature and their applications in community detection

L Fesser, SS de Haro Ivánez, K Devriendt… - Journal of Physics …, 2024 - iopscience.iop.org
The notion of curvature on graphs has recently gained traction in the networks community,
with the Ollivier–Ricci curvature (ORC) in particular being used for several tasks in network …

Transcriptomic Insight into the Pollen Tube Growth of Olea europaea L. subsp. europaea Reveals Reprogramming and Pollen-Specific Genes Including New …

A Bullones, AJ Castro, E Lima-Cabello… - Plants, 2023 - mdpi.com
The pollen tube is a key innovation of land plants that is essential for successful fertilisation.
Its development and growth have been profusely studied in model organisms, but in spite of …

Combining genetic and transcriptomic approaches to identify transporter-coding genes as likely responsible for a repeatable salt tolerance QTL in Citrus

MJ Asins, A Bullones, V Raga… - International Journal of …, 2023 - mdpi.com
The excessive accumulation of chloride (Cl−) in leaves due to salinity is frequently related to
decreased yield in citrus. Two salt tolerance experiments to detect quantitative trait loci …

PWN: enhanced random walk on a warped network for disease target prioritization

S Han, J Hong, SJ Yun, HJ Koo, TY Kim - BMC bioinformatics, 2023 - Springer
Background Extracting meaningful information from unbiased high-throughput data has
been a challenge in diverse areas. Specifically, in the early stages of drug discovery, a …

Community detection in the human connectome: Method types, differences and their impact on inference

SJ Brooks, VO Jones, H Wang, C Deng… - Human Brain …, 2024 - Wiley Online Library
Community structure is a fundamental topological characteristic of optimally organized brain
networks. Currently, there is no clear standard or systematic approach for selecting the most …

CE-GAN: Community Evolutionary Generative Adversarial Network for Alzheimer's Disease Risk Prediction

XA Bi, Z Yang, Y Huang, K Chen, Z Xing… - … on Medical Imaging, 2024 - ieeexplore.ieee.org
In the studies of neurodegenerative diseases such as Alzheimer's Disease (AD),
researchers often focus on the associations among multi-omics pathogeny based on …

Analyzing neural network robustness using graph curvature

S Tan, J Sia, P Bogdan, R Ivanov - … International Conference on …, 2024 - ieeexplore.ieee.org
This paper presents a new look at the neural network (NN) robustness problem, from the
point of view of graph theory analysis, specifically graph curvature. Graph curvature (eg …