Pleotropic effects of statins: the dilemma of wider utilization of statin

A Choudhary, U Rawat, P Kumar, P Mittal - The Egyptian Heart Journal, 2023 - Springer
Background Apart from reducing the circulating LDL-c and the number of cardiovascular
cases as well as fatalities, statins have auxiliary non–lipid-related or cholesterol …

Do statins induce or protect from acute kidney injury and chronic kidney disease: an update review in 2018

A Verdoodt, PM Honore, R Jacobs… - Journal of translational …, 2018 - degruyter.com
Statins essentially are cholesterol-lowering drugs that are extensively prescribed for primary
and secondary prevention of cardiovascular disease. Compelling evidence suggests that …

Statins: Complex outcomes but increasingly helpful treatment options for patients

N Mohammadkhani, S Gharbi, HF Rajani… - European Journal of …, 2019 - Elsevier
Statins are long known class of medicines and the most frequently prescribed drugs in
cardiovascular pharmacotherapy, widely ordered not only in patients suffering from …

[HTML][HTML] A wide scope, pan-comparative, systematic meta-analysis of the efficacy of prophylactic strategies for cardiac surgery-associated acute kidney injury

M Martín-Fernández, AG Casanova… - Biomedicine & …, 2024 - Elsevier
Acute kidney injury (AKI) is the most common complication of cardiac surgery. Cardiac
surgery-associated AKI (CSA-AKI) is caused by systemic and renal hemodynamic …

Hepatic dysfunction in patients who received acute DeBakey type I aortic dissection repair surgery: incidence, risk factors, and long-term outcomes

Z Wang, M Ge, C Chen, L Lu, L Zhang… - Journal of Cardiothoracic …, 2021 - Springer
Background Hepatic dysfunction (HD) increases the morbidity and mortality rates after
cardiac surgery. However, few studies have investigated the association between HD and …

Statins and the kidney: Friend or foe?

PM Honore, R Jacobs, I Hendrickx, E De Waele… - Blood …, 2017 - karger.com
Statins essentially are cholesterol-lowering drugs that are extensively prescribed for primary
and secondary prevention of cardiovascular disease. Compelling evidence suggests that …

Effect of lipid-lowering medications in patients with coronary artery bypass grafting surgery outcomes

C Shi, Z Zhang, J Goldhammer, D Li, B Kiaii… - BMC …, 2022 - Springer
Background Increased life expectancy and improved medical technology allow increasing
numbers of elderly patients to undergo cardiac surgery. Elderly patients may be at greater …

Recent perioperative pharmacological prevention of acute kidney injury after cardiac surgery: a narrative review

S Li, S Fu, Y Xiao, G Xu - American Journal of Cardiovascular Drugs, 2017 - Springer
Acute kidney injury (AKI) is a common and severe complication of cardiac surgery, and
related rates of both hospitalization and long-term mortality are increasing. A number of …

Peri-operative fluid strategy and post-operative acute kidney injury in cardiac surgery patients: any role for pre-operative statin therapy?

PM Honore, R Jacobs, I Hendrickx, E De Waele… - Critical Care, 2015 - Springer
Acute kidney injury (AKI) is a common complication associated with increased morbidity and
mortality in cardiac surgery patients. In this context, the recent paper by Kim et al., showing …

Is new-onset statin an apple and postoperative acute kidney injury mixed fruit?

BR Osswald, EH Blackstone - European Journal of Cardio …, 2016 - academic.oup.com
Without doubt, 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) lower
lipids in a large, clinically meaningful fashion. In the laboratory, they have a dizzying …