1, 25-Dihydroxvitamin D3 [1, 25 (OH) 2D3] is the hormonally active form of vitamin D. The
genomic mechanism of 1, 25 (OH) 2D3 action involves the direct binding of the 1, 25 (OH) …

Vitamin D is a precursor of the steroid hormone calcitriol that is crucial for bone and mineral
metabolism. Both the high prevalence of vitamin D deficiency in the general population and …

Objective To evaluate the breadth, validity, and presence of biases of the associations of
vitamin D with diverse outcomes. Design Umbrella review of the evidence across systematic …

Vitamin D plays a classical hormonal role in skeletal health by regulating calcium and
phosphorus metabolism. Vitamin D metabolites also have physiological functions in …

Vitamin D deficiency is typically caused by inadequate cutaneous synthesis secondary to
decreased exposure to sunlight. Serum levels of 25-hydroxyvitamin D l< 20 ng/ml are …

Vitamin D insufficiency affects almost 50% of the population worldwide. An estimated 1
billion people worldwide, across all ethnicities and age groups, have a vitamin D deficiency …

The aim of the present paper was to review the most important mechanisms explaining the
possible association of vitamin D deficiency and cardiovascular diseases, focusing on …

BACKGROUND: There is increasing evidence that, in addition to the well-known effects on
musculoskeletal health, vitamin D status may be related to a number of non-skeletal …

Background—A variety of studies carried out using either human subjects or laboratory
animals suggest that vitamin D and its analogues possess important beneficial activity in the …

The number of individuals aged 65 and older is expected to more than double from 2012 to
2060. The role of vitamin D in the prevention and treatment of diseases associated with …