The 1990s witnessed an expansion of the antifungal armamentarium to include 2 new azole
agents, fluconazole and itraconazole. These agents changed our approach to treating many …

Fungi may infect the cornea, orbit and other ocular structures. Species of Fusarium,
Aspergillus, Candida, dematiaceous fungi, and Scedosporium predominate. Diagnosis is …

Infections by Fusarium species frequently involve the skin, either as the primary or the
metastatic site. To better understand the pathophysiology of these infections, 43 new …

Treatments for invasive fungal infections remain unsatisfactory. We evaluated the efficacy,
tolerability, and safety of voriconazole as salvage treatment for 273 patients with refractory …

Fusarium species frequently implicated in human infections include F. solani, F. oxysporum
and F. moniliforme. Among immunocompetent patients, tissue breakdown (as caused by …

There is an increased awareness of the morbidity and mortality associated with fungal
infections caused by resistant fungi in various groups of patients. Epidemiological studies …

Background: Reports of resistance and intolerance to currently available antifungal agents
are increasing. Voriconazole is a broad-spectrum azole antifungal agent structurally derived …

Objective To investigate the penetration of voriconazole, a new-generation triazoleantifungal
agent, into the vitreous and aqueous humor after oral administration. Methods A prospective …

Background: Voriconazole has an important role to play in the prophylaxis and management
of fungal endophthalmitis and keratitis. New-generation triazoles, including voriconazole …

Purpose: To review the current state of evaluation and management of various forms of
endophthalmitis. Methods: A review of the literature is included, encompassing …