Chemically modified and conjugated antimicrobial peptides against superbugs
Antimicrobial resistance (AMR) is one of the greatest threats to human health that, by 2050,
will lead to more deaths from bacterial infections than cancer. New antimicrobial agents …
will lead to more deaths from bacterial infections than cancer. New antimicrobial agents …
Dimerization of antimicrobial peptides: a promising strategy to enhance antimicrobial peptide activity
EN Lorenzon, JP Piccoli… - Protein and peptide …, 2019 - ingentaconnect.com
Antimicrobial resistance is a global health problem with strong social and economic impacts.
The development of new antimicrobial agents is considered an urgent challenge. In this …
The development of new antimicrobial agents is considered an urgent challenge. In this …
Biomaterial‐interrelated bacterial sweeper: simplified self‐assembled octapeptides with double‐layered Trp zipper induces membrane destabilization and bacterial …
Y Fang, Y Zhu, L Li, Z Lai, N Dong, A Shan - Small Methods, 2021 - Wiley Online Library
Abstract Treatment of microbial‐associated infections continues to be hampered by impaired
antibacterial efficiency and the variability in nanomedicines. Herein, an octapeptide library …
antibacterial efficiency and the variability in nanomedicines. Herein, an octapeptide library …
Effect of an antimicrobial peptide on lateral segregation of lipids: a structure and dynamics study by neutron scattering
Antimicrobial peptides are one of the most promising classes of antibiotic agents for drug-
resistant bacteria. Although the mechanisms of their action are not fully understood, many of …
resistant bacteria. Although the mechanisms of their action are not fully understood, many of …
A critical review of short antimicrobial peptides from scorpion venoms, their physicochemical attributes, and potential for the development of new drugs
PA Fong-Coronado, V Ramirez… - The Journal of …, 2024 - Springer
Scorpion venoms have proven to be excellent sources of antimicrobial agents. However,
although many of them have been functionally characterized, they remain underutilized as …
although many of them have been functionally characterized, they remain underutilized as …
Interaction of the antimicrobial peptide aurein 1.2 and charged lipid bilayer
Aurein 1.2 is a potent antimicrobial peptide secreted by frog Litoria aurea. As a short
membrane-active peptide with only 13 amino acids in sequence, it has been found to be …
membrane-active peptide with only 13 amino acids in sequence, it has been found to be …
Interaction of a short antimicrobial peptide on charged lipid bilayer: A case study on aurein 1.2 peptide
S Qian, PA Zolnierczuk - BBA advances, 2022 - Elsevier
Abstract Aurein 1.2 (aurein) is a short but active α-helical antimicrobial peptide discovered in
Australian tree frogs (Litoria aurea). It shows inhibition on a broad spectrum of bacteria and …
Australian tree frogs (Litoria aurea). It shows inhibition on a broad spectrum of bacteria and …
Understanding the mechanism of action of peptide (p-BthTX-I) 2 derived from C-terminal region of phospholipase A2 (PLA2)-like bothropstoxin-I on Gram-positive and …
NA Santos-Filho, LM de Freitas, CT Dos Santos… - Toxicon, 2021 - Elsevier
Based on the antimicrobial activity of bothropstoxin-I (BthTX-I) and on the premise that a C-
terminal peptide of Lys49 myotoxin can reproduce the antimicrobial activity of the parent …
terminal peptide of Lys49 myotoxin can reproduce the antimicrobial activity of the parent …
Interaction of cationic antimicrobial peptides from Australian frogs with lipid membranes
S Zhu, MA Sani, F Separovic - Peptide Science, 2018 - Wiley Online Library
Cationic antimicrobial peptides (AMPs) from Australian frogs have been extensively studied
as alternatives to traditional antibiotics. Solid‐state NMR is used to characterize their effect …
as alternatives to traditional antibiotics. Solid‐state NMR is used to characterize their effect …
Antimicrobial activity and mechanism of action of a novel peptide present in the ecdysis process of centipede Scolopendra subspinipes subspinipes
E Chaparro-Aguirre, PJ Segura-Ramírez, FL Alves… - Scientific Reports, 2019 - nature.com
One of the most important cellular events in arthropods is the moulting of the cuticle
(ecdysis). This process allows them to grow until they reach sexual maturity. Nevertheless …
(ecdysis). This process allows them to grow until they reach sexual maturity. Nevertheless …