The role of microRNAs in epigenetic regulation of signaling pathways in neurological pathologies

PP Tregub, I Ibrahimli, AS Averchuk… - International journal of …, 2023 - mdpi.com
In recent times, there has been a significant increase in researchers' interest in the functions
of microRNAs and the role of these molecules in the pathogenesis of many multifactorial …

Unveiling the therapeutic potential of non-coding RNAs in stroke-induced tissue regeneration

A Waseem, AQ Khan, MA Khan, R Khan, S Uddin… - Stem Cells, 2023 - academic.oup.com
Stroke is a major contributor to mortality and impairment on a global scale, with few effective
treatments available. Aberrant expression of various non-coding RNAs (ncRNAs) has been …

MicroRNAs as biomarkers of brain injury in neonatal encephalopathy: an observational cohort study

F Dakroub, F Kobeissy, S Mondello, Z Yang, H Xu… - Scientific reports, 2024 - nature.com
Neonatal Encephalopathy (NE) is a major cause of lifelong disability and neurological
complications in affected infants. Identifying novel diagnostic biomarkers in this population …

Astrocytes in ischemic stroke: crosstalk in central nervous system and therapeutic potential

J Liu, Y Guo, Y Zhang, X Zhao, R Fu, S Hua… - …, 2024 - Wiley Online Library
In the central nervous system (CNS), a large group of glial cells called astrocytes play
important roles in both physiological and disease conditions. Astrocytes participate in the …

MiRNAs as potential therapeutic targets and biomarkers for non-traumatic intracerebral hemorrhage

I Gareev, O Beylerli, B Zhao - Biomarker Research, 2024 - Springer
Non-traumatic intracerebral hemorrhage (ICH) is the most common type of hemorrhagic
stroke, most often occurring between the ages of 45 and 60. Hypertension is most often the …

The role of miR-20 in Health and disease of the central nervous system

I Arzhanov, K Sintakova, N Romanyuk - Cells, 2022 - mdpi.com
Current understanding of the mechanisms underlying central nervous system (CNS) injury is
limited, and traditional therapeutic methods lack a molecular approach either to prevent …

Sex differences in cognitive impairment after focal ischemia in middle-aged rats and the effect of iv miR-20a-3p treatment

D Sampath, TE Branyan, KG Markowsky, R Gunda… - Neurobiology of …, 2023 - Elsevier
Stroke is a major cause of death and disability worldwide and is also a leading cause of
vascular dementia and Alzheimer's disease, with older women experiencing accelerated …

[HTML][HTML] Peripheral, but not central, IGF-1 treatment attenuates stroke-induced cognitive impairment in middle-aged female Sprague Dawley rats: The gut as a …

Y El-Hakim, KK Mani, KA Pickle, Z Akbari… - Brain, Behavior, and …, 2024 - Elsevier
Stroke results in immediate sensory or motor disability and increases the risk for long term
cognitive-affective impairments. Thus, therapies are urgently needed to improve quality of …

Real-time PCR quantification of 87 miRNAs from cerebrospinal fluid: miRNA dynamics and association with extracellular vesicles after severe traumatic brain injury

LV Seršić, VK Alić, M Biberić, S Zrna, T Jagoić… - International Journal of …, 2023 - mdpi.com
Severe traumatic brain injury (sTBI) is an intracranial damage triggered by external force,
most commonly due to falls and traffic accidents. The initial brain injury can progress into a …

Advances in neuroprotective therapy for acute ischemic stroke

Y Yang, D Guo, Y Liu, Y Li - Exploration of Neuroprotective …, 2024 - explorationpub.com
Acute ischemic stroke (AIS) is the leading cause of disability worldwide, and recanalization
therapy is significant in the hyperacute phase of AIS. However, reperfusion injury and …