Imbalanced GSH/ROS and sequential cell death

T Liu, L Sun, Y Zhang, Y Wang… - Journal of Biochemical …, 2022 - Wiley Online Library
Reactive oxygen species (ROS) are produced in cells during metabolic processes.
Excessive intracellular ROS may react with large biomolecules, such as DNA, RNA …

[HTML][HTML] An update on the effects of vitamin D on the immune system and autoimmune diseases

C Sîrbe, S Rednic, A Grama, TL Pop - International journal of molecular …, 2022 - mdpi.com
Vitamin D intervenes in calcium and phosphate metabolism and bone homeostasis.
Experimental studies have shown that 1, 25-dihydroxyvitamin D (calcitriol) generates …

Redox imbalance links COVID-19 and myalgic encephalomyelitis/chronic fatigue syndrome

BD Paul, MD Lemle, AL Komaroff… - Proceedings of the …, 2021 - National Acad Sciences
Although most patients recover from acute COVID-19, some experience postacute sequelae
of severe acute respiratory syndrome coronavirus 2 infection (PASC). One subgroup of …

[HTML][HTML] Vitamin D's effect on immune function

PJ Martens, C Gysemans, A Verstuyf, C Mathieu - Nutrients, 2020 - mdpi.com
Ever since its discovery by Windhaus, the importance of the active metabolite of vitamin D (1,
25-dihydroxyvitamin D 3; 1, 25-(OH) 2D 3) has been ever expanding. In this review, the …

Emerging role of vitamin D in autoimmune diseases: An update on evidence and therapeutic implications

G Murdaca, A Tonacci, S Negrini, M Greco, M Borro… - Autoimmunity …, 2019 - Elsevier
Vitamin D plays a key role in in calcium homeostasis and, thus, provides an important
support in bone growth by aiding in the mineralization of the collagen matrix. However …

[HTML][HTML] Analysis of association between vitamin D deficiency and insulin resistance

I Szymczak-Pajor, A Śliwińska - Nutrients, 2019 - mdpi.com
Recent evidence revealed extra skeleton activity of vitamin D, including prevention from
cardiometabolic diseases and cancer development as well as anti-inflammatory properties …

[HTML][HTML] The molecular mechanisms by which vitamin D prevents insulin resistance and associated disorders

I Szymczak-Pajor, J Drzewoski, A Śliwińska - International journal of …, 2020 - mdpi.com
Numerous studies have shown that vitamin D deficiency is very common in modern societies
and is perceived as an important risk factor in the development of insulin resistance and …

Nutrients and oxidative stress: friend or foe?

BL Tan, ME Norhaizan… - Oxidative medicine and …, 2018 - Wiley Online Library
There are different types of nutritionally mediated oxidative stress sources that trigger
inflammation. Much information indicates that high intakes of macronutrients can promote …

[HTML][HTML] Mechanisms involved in the relationship between vitamin D and insulin resistance: impact on clinical practice

V Contreras-Bolívar, B García-Fontana… - Nutrients, 2021 - mdpi.com
Recent evidence has revealed anti-inflammatory properties of vitamin D as well as extra-
skeletal activity. In this context, vitamin D seems to be involved in infections, autoimmune …

Antioxidant, anti-inflammatory and immunomodulatory roles of vitamins in COVID-19 therapy

AM Pisoschi, A Pop, F Iordache, L Stanca… - European Journal of …, 2022 - Elsevier
Abstract oxidative stress is caused by an abundant generation of reactive oxygen species,
associated to a diminished capacity of the endogenous systems of the organism to …