Bacterial contamination of the uterine lumen is common in cattle after parturition, often
leading to infection and uterine disease. Clinical disease can be diagnosed and scored by …

The mucosal immune system in the female reproductive tract (FRT) has evolved to meet the
unique requirements of dealing with sexually transmitted bacterial and viral pathogens …

Background Endometriosis is a multifactorial disease that mainly affects women of
reproductive age. The exact pathogenesis of this disease is still debatable. The role of …

Oestrogens are pivotal in ovarian follicular growth, development and function, with
fundamental roles in steroidogenesis, nurturing the oocyte and ovulation. Infections with …

BACKGROUND Pre-eclampsia is a syndrome of heterogeneous origin characterized by
deficient placentation due to the inability of the cytotrophoblast to acquire an invasive …

Infection of the bovine endometrium with Gram-negative bacteria commonly causes uterine
disease. Toll-like receptor 4 (TLR4) on cells of the immune system bind Gram-negative …

Prostaglandins have a central role in many endocrine functions in mammals, including
regulation of the life span of the corpus luteum by prostaglandin F2α (PGF) and …

The active form of vitamin D, 1, 25-dihydroxyvitamin D3 (1, 25 [OH] 2D3) is a potent
immunomodulatory seco-steroid. We have demonstrated that several components of vitamin …

Escherichia coli infection of the endometrium causes uterine disease after parturition and is
associated with prolonged luteal phases of the ovarian cycle in cattle. Termination of the …

Natural products have been used in medicine for thousands of years. Given their potential
health benefits, they have gained significant popularity in recent times. The administration of …