Ca2+ dynamics in interstitial cells: foundational mechanisms for the motor patterns in the gastrointestinal tract
The gastrointestinal (GI) tract displays multiple motor patterns that move nutrients and
wastes through the body. Smooth muscle cells (SMCs) provide the forces necessary for GI …
wastes through the body. Smooth muscle cells (SMCs) provide the forces necessary for GI …
T-type calcium channels in cancer
L Antal, M Martin-Caraballo - Cancers, 2019 - mdpi.com
Although voltage-activated Ca2+ channels are a common feature in excitable cells, their
expression in cancer tissue is less understood. T-type Ca2+ channels are particularly …
expression in cancer tissue is less understood. T-type Ca2+ channels are particularly …
The enteric nervous system
KA Sharkey, GM Mawe - Physiological reviews, 2023 - journals.physiology.org
Of all the organ systems in the body, the gastrointestinal tract is the most complicated in
terms of the numbers of structures involved, each with different functions, and the numbers …
terms of the numbers of structures involved, each with different functions, and the numbers …
Metalloendopeptidase ADAM-like Decysin 1 (ADAMDEC1) in Colonic Subepithelial PDGFRα+ Cells Is a New Marker for Inflammatory Bowel Disease
Metalloendopeptidase ADAM-Like Decysin 1 (ADAMDEC1) is an anti-inflammatory
peptidase that is almost exclusively expressed in the gastrointestinal (GI) tract. We have …
peptidase that is almost exclusively expressed in the gastrointestinal (GI) tract. We have …
Sympathetic input to multiple cell types in mouse and human colon produces region-specific responses
KM Smith-Edwards, BS Edwards, CM Wright… - Gastroenterology, 2021 - Elsevier
Background & Aims The colon is innervated by intrinsic and extrinsic neurons that
coordinate functions necessary for digestive health. Sympathetic input suppresses colon …
coordinate functions necessary for digestive health. Sympathetic input suppresses colon …
Importance of clitellar tissue in the regeneration ability of earthworm Eudrilus eugeniae
S Paul, S Balakrishnan, A Arumugaperumal… - Functional & Integrative …, 2022 - Springer
Among the annelids, earthworms are renowned for their phenomenal ability to regenerate
the lost segments. The adult earthworm Eudrilus eugeniae contains 120 segments and the …
the lost segments. The adult earthworm Eudrilus eugeniae contains 120 segments and the …
[HTML][HTML] A hierarchical and collaborative BRD4/CEBPD partnership governs vascular smooth muscle cell inflammation
Bromodomain protein BRD4 reads histone acetylation (H3K27ac), an epigenomic mark of
transcription enhancers. CCAAT enhancer binding protein delta (CEBPD) is a transcription …
transcription enhancers. CCAAT enhancer binding protein delta (CEBPD) is a transcription …
[HTML][HTML] Norepinephrine has dual effects on human colonic contractions through distinct subtypes of alpha 1 adrenoceptors
M Kurahashi, Y Kito, M Hara, H Takeyama… - Cellular and molecular …, 2020 - Elsevier
Background & Aims Colonic musculature contain smooth muscle cells (SMC), interstitial
cells of Cajal (ICC), and platelet-derived growth factor receptor α+ cells (PDGFRα+ cells) …
cells of Cajal (ICC), and platelet-derived growth factor receptor α+ cells (PDGFRα+ cells) …
[HTML][HTML] Single Nucleus Sequencing of Human Colon Myenteric Plexus–Associated Visceral Smooth Muscle Cells, Platelet Derived Growth Factor Receptor Alpha …
Background and Aims Smooth muscle cells (SMCs), interstitial cells of Cajal (ICCs), and
platelet-derived growth factor receptor alpha (PDGFRα+) cells (PαCs) form a functional …
platelet-derived growth factor receptor alpha (PDGFRα+) cells (PαCs) form a functional …
[HTML][HTML] A novel post-synaptic signal pathway of sympathetic neural regulation of murine colonic motility
Transcriptome data revealed α1 adrenoceptors (ARs) expression in platelet-derived growth
factor receptor α+ cells (PDGFRα+ cells) in murine colonic musculature. The role of …
factor receptor α+ cells (PDGFRα+ cells) in murine colonic musculature. The role of …