Construction of local drug delivery system on titanium-based implants to improve osseointegration

F Meng, Z Yin, X Ren, Z Geng, J Su - Pharmaceutics, 2022 - mdpi.com
Titanium and its alloys are the most widely applied orthopedic and dental implant materials
due to their high biocompatibility, superior corrosion resistance, and outstanding mechanical …

Soft and Hard Tissue Integration around Percutaneous Bone-Anchored Titanium Prostheses: Toward Achieving Holistic Biointegration

S Shrivas, H Samaur, V Yadav… - ACS Biomaterials Science …, 2024 - ACS Publications
A holistic biointegration of percutaneous bone-anchored metallic prostheses with both hard
and soft tissues dictates their longevity in the human body. While titanium (Ti) has nearly …

Photoelectrons sequentially regulate antibacterial activity and osseointegration of titanium implants

Y Tang, K Wang, B Wu, K Yao, S Feng… - Advanced …, 2024 - Wiley Online Library
Titanium implants are widely used; however, implantation occasionally fails due to infections
during the surgery or poor osseointegration after the surgery. To solve the problem, an …

Layer-by-layer self-assembly and clinical application in orthopedics

X Ma, D Zhao, Y Xiang, Y Hua, W Zhao, Y Cui… - Journal of Materials …, 2023 - Elsevier
Orthopedic implants for the treatment of bone defects from various causes have been
challenged by insufficient osseointegration, bacterial infection, oxidative stress, immune …

Unraveling the Applicability of LbL Coatings for Drug Delivery in Dental Implant-Related Infection Treatment

MM Alves Pereira, R Piazza, AP Santana… - ACS Biomaterials …, 2024 - ACS Publications
Peri-implantitis is an inflammatory condition caused by bacterial biofilms adhered on dental
implant surfaces that cause progressive tissue destruction from the host's inflammatory …

Comprehensive Overview of Interface Strategies in Implant Osseointegration

X Lu, Y Zhao, X Peng, C Lu, Z Wu, H Xu… - Advanced Functional …, 2024 - Wiley Online Library
With the improvement of implant design and the expansion of application scenarios,
orthopedic implants have become a common surgical option for treating fractures and end …

Growth factor-functionalized titanium implants for enhanced bone regeneration: A review

Z Che, Q Sun, Z Zhao, Y Wu, H Xing, K Song… - International Journal of …, 2024 - Elsevier
Titanium and titanium alloys are widely favored materials for orthopedic implants due to their
exceptional mechanical properties and biological inertness. The additional benefit of …

Smart self-defensive coatings with bacteria-triggered antimicrobial response for medical devices

MA Cassa, P Gentile, J Girón-Hernández… - Biomaterials …, 2024 - pubs.rsc.org
Bacterial colonization and biofilm formation on medical devices represent one of the most
urgent and critical challenges in modern healthcare. These issues not only pose serious …

Implant surface modifications and their impact on osseointegration and peri‐implant diseases through epigenetic changes: A scoping review

MF Kunrath, C Garaicoa‐Pazmino… - Journal of …, 2024 - Wiley Online Library
Dental implant surfaces and their unique properties can interact with the surrounding oral
tissues through epigenetic cues. The present scoping review provides current perspectives …

Hybrid coatings on dental and orthopedic titanium implants: Current advances and challenges

W Tang, NG Fischer, X Kong, T Sang, Z Ye - BMEMat, 2024 - Wiley Online Library
Dental and orthopedic titanium implants are successfully and widely used but still face
challenges due to complications leading to high treatment cost, morbidity, and even …