Abstract Introduction Immunoglobulin A (IgA) deficiency is the most common primary
immunodeficiency defined as decreased serum level of IgA in the presence of normal levels …

Selective immunoglobulin A deficiency (SI g AD) is the most common primary antibody
deficiency. Although more patients with SI g AD are asymptomatic, selected patients suffer …

The International Collaboration in Asthma, Allergy and Immunology initiated an international
coalition among the American Academy of Allergy, Asthma & Immunology; the European …

Most autosomal genetic causes of childhood-onset hypogammaglobulinemia are currently
not well understood. Most affected individuals are simplex cases, but both autosomal …

The American Academy of Allergy, Asthma & Immunology (AAAAI) and the American
College of Allergy, Asthma & Immunology (ACAAI) have jointly accepted responsibility for …

Fifty years have elapsed since the term common variable immunodeficiency (CVID) was
introduced to accommodate the many and varied antibody deficiencies being identified in …

The life span of patients with primary and secondary immunodeficiency is increasing due to
recent improvements in therapeutic strategies. While the incidence of primary …

Common variable immunodeficiency (CVID), characterized by recurrent infections, is the
most prevalent symptomatic antibody deficiency. In∼ 90% of CVID-affected individuals, no …

Selective immunoglobulin A deficiency (SIgAD) is the most common primary
immunodeficiency, defined as an isolated deficiency of IgA (less than 0.07 g/L). Although the …

The transcriptional programs that guide lymphocyte differentiation depend on the precise
expression and timing of transcription factors (TFs). The TF BACH2 is essential for T and B …