Curcumin combination chemotherapy: The implication and efficacy in cancer

BL Tan, ME Norhaizan - Molecules, 2019 - mdpi.com
Many chemotherapeutic drugs have been used for the treatment of cancer, for instance,
doxorubicin, irinotecan, 5-fluorouracil, cisplatin, and paclitaxel. However, the effectiveness of …

Saponins as cytotoxic agents: An update (2010–2021). Part II—Triterpene saponins

I Podolak, K Grabowska, D Sobolewska… - Phytochemistry …, 2023 - Springer
Saponins make up an important group of natural glycosidic compounds which are
distinguished by triterpene or steroidal aglycone. Although widely distributed in terrestrial …

Implication of nano-antioxidant therapy for treatment of hepatocellular carcinoma using PLGA nanoparticles of rutin

P Pandey, M Rahman, PC Bhatt, S Beg, B Paul… - …, 2018 - Taylor & Francis
Aim: The present work describes the development of poly (lactic co-glycolic acid)(PLGA)
nanoparticles (NPs) of rutin (RT) for the treatment of hepatocellular carcinoma in rats …

Glycosides from medicinal plants as potential anticancer agents: emerging trends towards future drugs

H Khan, M Saeedi, SM Nabavi… - Current medicinal …, 2019 - ingentaconnect.com
Background: Cancer continues to be a global burden, despite the advancement of various
technological and pharmaceutical improvements over the past two decades. Methods for …

Fabrication, optimization, and characterization of umbelliferone β-D-galactopyranoside-loaded PLGA nanoparticles in treatment of hepatocellular carcinoma: in vitro …

V Kumar, PC Bhatt, M Rahman… - International Journal …, 2017 - Taylor & Francis
Umbelliferone β-D-galactopyranoside (UFG), isolated from plants, exhibits promising
inhibitory action on numerous diseases. The present research was initiated to develop a …

Ganoderic acid loaded nano-lipidic carriers improvise treatment of hepatocellular carcinoma

M Rahman, SA Al-Ghamdi, KS Alharbi, S Beg… - Drug Delivery, 2019 - Taylor & Francis
This work evaluates nano-lipid carrier of ganoderic acid (GA) and molecular docking on
various cancer signaling pathways, an attempt to improve the hepatic condition associated …

Attenuation of neurobehavioral and neurochemical abnormalities in animal model of cognitive deficits of Alzheimer's disease by fermented soybean nanonutraceutical

PC Bhatt, S Pathak, V Kumar, BP Panda - Inflammopharmacology, 2018 - Springer
The present study was performed to evaluate the efficacy of nanonutraceuticals (NN) for
attenuation of neurobehavioral and neurochemical abnormalities in Alzheimer's disease …

The critical role of the phytosterols in modulating tumor microenvironment via multiple signaling: A comprehensive molecular approach

AU Khan, A Khan, B Shal, S Khan, M Khan… - Phytotherapy …, 2023 - Wiley Online Library
Cancer is the leading cause of mortality and morbidity worldwide, and its cases are rapidly
increasing every year. Several factors contribute to the development of tumorigenesis …

Isatin counteracts diethylnitrosamine/2-acetylaminofluorene-induced hepatocarcinogenesis in male Wistar rats by upregulating anti-inflammatory, antioxidant, and …

NG Tawfik, WR Mohamed, HS Mahmoud, MA Alqarni… - Antioxidants, 2022 - mdpi.com
Hepatocellular carcinoma (HCC) represents around 85% of all known types of liver cancers
and is estimated to be the fifth most common cause of cancer-related death worldwide. The …

The anticarcinogenic effect of eugenol on lung cancer induced by diethylnitrosamine/2-acetylaminofluorene in Wistar rats: Insight on the mechanisms of action

HM Morsy, OM Ahmed, KMA Zoheir, A Abdel-Moneim - Apoptosis, 2023 - Springer
This study was designed to assess the ameliorative effects of eugenol and to propose the
possible mechanisms of action of eugenol in diethylnitrosamine (DENA) …