This report explores the available curative molecules directed against hepatocellular
carcinoma (HCC). Limited efficiency as well as other drawbacks of existing molecules led to …

Liver disease, involving a wide range of liver pathologies from fatty liver, hepatitis, and
fibrosis to cirrhosis and hepatocellular carcinoma, is a serious health problem worldwide. In …

Cancer is one of the leading causes of death worldwide and a major global health problem.
In recent decades, the rates of both mortality and morbidity of cancer have rapidly increased …

The flavonoids, baicalin, and its aglycone baicalein possess multi-fold therapeutic properties
and are mainly found in the roots of Oroxylum indicum (L.) Kurz and Scutellaria baicalensis …

Abstract Baicalein (5, 6, 7-trihydroxy-2-phenyl-4H-1-benzopyran-4-one) is a flavonoid
compound derived from the roots of Scutellaria baicalensis. It has historically been used in …

Autophagy, which is a conserved biological process and essential mechanism in
maintaining homeostasis and metabolic balance, enables cells to degrade cytoplasmic …

Abstract UNC-51-like kinase 1 (ULK1), as a serine/threonine kinase, is an autophagic
initiator in mammals and a homologous protein of autophagy related protein (Atg) 1 in yeast …

Simple Summary Cancer is a multifactorial disease characterized by excessive cell
proliferation in a specific organ. The most common treatments include chemotherapy …

Autophagy is a conserved biological phenomenon that maintains cellular homeostasis
through the clearing of damaged cellular components under cellular stress and offers the …

Coptisine is isoquinoline alkaloid derived from Coptidis Rhizoma and is known to have
potential anti-cancer activity toward various carcinomas. Targeting autophagy is one of the …