Revised consensus statement on the preventive and symptomatic care of patients with leukodystrophies

LA Adang, O Sherbini, L Ball, M Bloom… - Molecular genetics and …, 2017 - Elsevier
Leukodystrophies are a broad class of genetic disorders that result in disruption or
destruction of central myelination. Although the mechanisms underlying these disorders are …

Consensus statement on preventive and symptomatic care of leukodystrophy patients

K Van Haren, JL Bonkowsky, G Bernard… - Molecular genetics and …, 2015 - Elsevier
Leukodystrophies are inherited disorders whose primary pathophysiology consists of
abnormal deposition or progressive disruption of brain myelin. Leukodystrophy patients …

Megalencephalic leukoencephalopathy with subcortical cysts: characterization of disease variants

EMC Hamilton, P Tekturk, F Cialdella… - Neurology, 2018 - AAN Enterprises
Objective To provide an overview of clinical and MRI characteristics of the different variants
of the leukodystrophy megalencephalic leukoencephalopathy with subcortical cysts (MLC) …

Association of diagnosis of leukodystrophy with race and ethnicity among pediatric and adolescent patients

JL Bonkowsky, J Wilkes, T Bardsley… - JAMA Network …, 2018 - jamanetwork.com
Importance Inherited leukodystrophies are a group of neurological diseases affecting myelin
that cause significant morbidities and death. Timely and correct diagnosis is important for …

[HTML][HTML] The International Working Group on Neurotransmitter related Disorders (iNTD): A worldwide research project focused on primary and secondary …

T Opladen, E Cortès-Saladelafont… - Molecular Genetics and …, 2016 - Elsevier
Introduction Neurotransmitters are chemical messengers that enable communication
between the neurons in the synaptic cleft. Inborn errors of neurotransmitter biosynthesis …

Leukodystrophies in children: diagnosis, care, and treatment

JL Bonkowsky, S Keller, JK Capal, T Lotze… - …, 2021 - publications.aap.org
Leukodystrophies are a group of genetically determined disorders that affect development or
maintenance of central nervous system myelin. Leukodystrophies have an incidence of at …

The leukodystrophies

HB Gordon, A Letsou, JL Bonkowsky - Seminars in neurology, 2014 - thieme-connect.com
Leukodystrophies are a group of genetically determined disorders that affect development or
maintenance of central nervous system myelin. Leukodystrophies have a reported incidence …

Reliability of the telemedicine application of the Gross Motor Function Measure-88 in patients with leukodystrophy

F Gavazzi, L Adang, A Waldman, AK Jan, G Liu… - Pediatric …, 2021 - Elsevier
Background Leukodystrophies are a rare class of disorders characterized by severe
neuromotor disability. There is a strong need for research regarding the functional status of …

Hospitalization burden and incidence of Krabbe disease

G Ghabash, J Wilkes, BJ Barney… - Journal of child …, 2022 - journals.sagepub.com
Objective: The purpose of our study was to understand the healthcare burden and incidence
of Krabbe disease (Krabbe). Methods: Retrospective analysis of Krabbe patients identified …

Networking across borders for individuals with organic acidurias and urea cycle disorders: the E-IMD consortium

S Kölker, D Dobbelaere, J Häberle, P Burgard… - JIMD Reports, Volume …, 2015 - Springer
Background: Patients with organic acidurias (OAD) and urea cycle disorders (UCD) are at
increased risk of disability, impaired quality of life and reduced life expectancy. Clinical care …