The interaction of coagulation factors with the perivascular environment affects the
development of disease in ways that extend beyond their traditional roles in the acute …

Proprotein convertase subtilisin/kexin Type 9 (PCSK9) is now identified as an important and
major player in hypercholesterolaemia and atherosclerosis pathophysiology. PCSK9 …

Diabetes mellitus (DM) is characterized by fasting hyperglycaemia and a high risk of
atherothrombotic disorders affecting the coronary, cerebral and peripheral arterial trees. The …

Peripheral artery disease (PAD), which consists of partial or complete obstruction of the
arteries in the lower limbs, is one of the most common manifestations of atherosclerosis …

Atherothrombotic complications are the main cause of mortality in subjects with diabetes.
Premature atherosclerosis, increased platelet reactivity and activation of coagulation factors …

Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), also known as coronavirus
disease 2019 (COVID-19)-induced infection, is strongly associated with various …

Atherothrombosis, characterised by atherosclerotic lesion disruption with superimposed
thrombus formation, is the major cause of acute coronary syndromes (ACS) and …

Obesity is associated with an increased incidence of insulin resistance (IR), type 2 diabetes
mellitus and cardiovascular diseases. The increased risk for cardiovascular diseases could …

The key concept of proteomics (looking at many proteins at once) opens new avenues in the
search for clinically useful biomarkers of disease, treatment response and ageing. As the …

Background Numerous studies have found that ambient air pollution has been associated
with cardiovascular disease exacerbation. Objectives Given previous findings, we …