Cell death is essential for a plethora of physiological processes, and its deregulation
characterizes numerous human diseases. Thus, the in-depth investigation of cell death and …

Mitochondria are most important organelles in the survival of eukaryotic aerobic cells
because they are the primary producers of ATP, regulators of ion homeostasis or redox …

Carbon dots (CDs) have emerged as promising nanomaterials for bioimaging-guided
photodynamic therapy (PDT). However, designing red-emissive CDs (RCDs) with tunable …

Currently, photosensitizers (PSs) that are microenvironment responsive and hypoxia active
are scarcely available and urgently desired for antitumor photodynamic therapy (PDT) …

Tracking the dynamics of mitochondrial morphology has attracted much research interest
because of its involvement in early stage apoptosis and degenerative conditions. To follow …

Different types of cell death are often defined by morphological criteria, without a clear
reference to precise biochemical mechanisms. The Nomenclature Committee on Cell Death …

Different cell death types are defined by morphological criteria, without a clear reference to
precise biochemical mechanisms. The Nomenclature Committee on Cell Death (NCCD) …

ATG12, an ubiquitin-like modifier required for macroautophagy, has a single known
conjugation target, another autophagy regulator called ATG5. Here, we identify ATG3 as a …

Purpose: Cisplatin adducts to nuclear DNA (nDNA) are felt to be the molecular lesions that
trigger apoptosis, but the mechanism linking nDNA adduct formation and cell death is …

Hepatitis C Virus (HCV) induces intracellular events that trigger mitochondrial dysfunction
and promote host metabolic alterations. Here, we investigated selective autophagic …