Icariin: A promising natural product in biomedicine and tissue engineering

Z Seyedi, MS Amiri, V Mohammadzadeh… - Journal of Functional …, 2023 - mdpi.com
Among scaffolds used in tissue engineering, natural biomaterials such as plant-based
materials show a crucial role in cellular function due to their biocompatibility and chemical …

[HTML][HTML] Pharmacological mechanism of natural drugs and their active ingredients in the treatment of arrhythmia via calcium channel regulation

X Zhang, Y Gao, Y Zhou, Z Liu, R Liu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Arrhythmia is characterized by abnormal heartbeat rhythms and frequencies caused by
heart pacing and conduction dysfunction. Arrhythmia is the leading cause of death in …

Ti3C2Tx@ PLGA/Icaritin microspheres-modified PLGA/β-TCP scaffolds modulate Icaritin release to enhance bone regeneration through near-infrared response

C Gu, H Chen, Y Zhao, H Xi, X Tan, P Xue… - Biomedical …, 2024 - iopscience.iop.org
Porous poly (lactic-co-glycolic acid)/β-tricalcium phosphate/Icaritin (PLGA/β-TCP/ICT, PTI)
scaffold is a tissue engineering scaffold based on PLGA/β-TCP (PT) containing Icaritin, the …

Role of microglia/macrophage polarisation in intraocular diseases

H Li, B Li, Y Zheng - International Journal of Molecular …, 2024 - spandidos-publications.com
Macrophages form a crucial component of the innate immune system, and their activation is
indispensable for various aspects of immune and inflammatory processes, tissue repair, and …

Natural products: protective effects against ischemia-induced retinal injury

Q He, L Xiao, Y Shi, W Li, X Xin - Frontiers in Pharmacology, 2023 - frontiersin.org
Ischemic retinal damage, a common condition associated with retinal vascular occlusion,
glaucoma, diabetic retinopathy, and other eye diseases, threatens the vision of millions of …

Neuroprotective mechanism of icariin on hypoxic ischemic brain damage in neonatal mice

M Wang, X Yang, Q Zhou, Y Guo… - Oxidative Medicine …, 2022 - Wiley Online Library
Objective. Our previous results showed that icariin (ICA) could inhibit apoptosis and provide
neuroprotection against hypoxic‐ischemic brain damage (HIBD) in neonatal mice, but the …

Effects of environmental heat load on endocannabinoid system components in adipose tissue of high yielding dairy cows

G Kra, JR Daddam, U Moallem, H Kamer, M Ahmad… - Animals, 2022 - mdpi.com
Simple Summary We hypothesized that environmental heat load (HL) may affect the
endocannabinoid system (ECS), a central regulator of metabolism and the stress response …

[HTML][HTML] Ischemic Optic Neuropathy: A Review of Current and Potential Future Pharmacotherapies

O Badla, BA Badla, A Almobayed, C Mendoza… - Pharmaceuticals, 2024 - mdpi.com
The treatment of arteritic anterior ischemic optic neuropathy (AAION), non-arteritic ischemic
optic neuropathy (NAAION), and posterior ischemic optic neuropathy (PION) is a topic of …

Neuroprotective Effects of Erinacine A on an Experimental Model of Traumatic Optic Neuropathy

CL Hsu, YT Wen, TC Hsu, CC Chen, LY Lee… - International Journal of …, 2023 - mdpi.com
Erinacine A (EA), a natural neuroprotectant, is isolated from a Chinese herbal medicine,
Hericium erinaceus. The aim of this study was to investigate the neuroprotective effects of …

[HTML][HTML] Icariin accelerates bone regeneration by inducing osteogenesis-angiogenesis coupling in rats with type 1 diabetes mellitus

S Zheng, GY Hu, JH Li, J Zheng, YK Li - World Journal of Diabetes, 2024 - ncbi.nlm.nih.gov
BACKGROUND Icariin (ICA), a natural flavonoid compound monomer, has multiple
pharmacological activities. However, its effect on bone defect in the context of type 1 …