The biology and mathematical modelling of glioma invasion: a review
JCL Alfonso, K Talkenberger… - Journal of the …, 2017 - royalsocietypublishing.org
Adult gliomas are aggressive brain tumours associated with low patient survival rates and
limited life expectancy. The most important hallmark of this type of tumour is its invasive …
limited life expectancy. The most important hallmark of this type of tumour is its invasive …
Necrotic reshaping of the glioma microenvironment drives disease progression
Glioblastoma is the most common primary brain tumor and has a dismal prognosis. The
development of central necrosis represents a tipping point in the evolution of these tumors …
development of central necrosis represents a tipping point in the evolution of these tumors …
Patch-based convolutional neural network for whole slide tissue image classification
Abstract Convolutional Neural Networks (CNN) are state-of-the-art models for many image
classification tasks. However, to recognize cancer subtypes automatically, training a CNN on …
classification tasks. However, to recognize cancer subtypes automatically, training a CNN on …
[HTML][HTML] The tumor microenvironment strongly impacts master transcriptional regulators and gene expression class of glioblastoma
The Cancer Genome Atlas (TCGA) project has generated gene expression data that divides
glioblastoma (GBM) into four transcriptional classes: proneural, neural, classical, and …
glioblastoma (GBM) into four transcriptional classes: proneural, neural, classical, and …
Glioblastoma stem cells are regulated by interleukin-8 signaling in a tumoral perivascular niche
DW Infanger, YJ Cho, BS Lopez, S Mohanan, SC Liu… - Cancer research, 2013 - AACR
Glioblastoma multiforme contains a subpopulation of cancer stem–like cells (CSC) believed
to underlie tumorigenesis and therapeutic resistance. Recent studies have localized CSCs …
to underlie tumorigenesis and therapeutic resistance. Recent studies have localized CSCs …
[HTML][HTML] PDA-based drug delivery nanosystems: a potential approach for glioma treatment
H Wu, M Wei, Y Xu, Y Li, X Zhai, P Su… - International journal …, 2022 - ncbi.nlm.nih.gov
Glioma is characterized by high mortality and low postoperative survival. Despite the
availability of various therapeutic approaches and molecular typing, the treatment failure …
availability of various therapeutic approaches and molecular typing, the treatment failure …
Machine-based morphologic analysis of glioblastoma using whole-slide pathology images uncovers clinically relevant molecular correlates
Pathologic review of tumor morphology in histologic sections is the traditional method for
cancer classification and grading, yet human review has limitations that can result in low …
cancer classification and grading, yet human review has limitations that can result in low …
Biomarker-driven diagnosis of diffuse gliomas
The diffuse gliomas are primary central nervous system tumors that arise most frequently in
the cerebral hemispheres of adults. They are currently classified as astrocytomas …
the cerebral hemispheres of adults. They are currently classified as astrocytomas …
Molecular pathways in gliomagenesis and their relevance to neuropathologic diagnosis
Gliomas are a large and diverse group of primary brain tumors that include those that are
diffusely infiltrative and others that are well-circumscribed and low grade. Diffuse gliomas …
diffusely infiltrative and others that are well-circumscribed and low grade. Diffuse gliomas …