Conduct disorder is a childhood behaviour disorder that is characterized by persistent
aggressive or antisocial behaviour that disrupts the child's environment and impairs his or …

Recent research shows that blunted cardiovascular and cortisol reactions to acute
psychological stress are associated with adverse behavioural and health outcomes …

This review aims to discuss the evidence supporting the link between chronic stress,
cognitive function and mental health. Over the years, the associations between these …

Coping, defined as action-oriented and intrapsychic efforts to manage the demands created
by stressful events, is coming to be recognized both for its significant impact on stress …

In recent years, there has been increasing interest in research on geographical variation in
the incidence of schizophrenia and other psychoses. In this paper, we review the evidence …

Stressful stimuli evoke complex endocrine, autonomic, and behavioral responses that are
extremely variable and specific depending on the type and nature of the stressors. We first …

• Genetic and environmental influences modulating risk of substance use disorders change
developmentally and across the lifespan.• Genes involved in vulnerability to addictions …

This article presents evidence suggesting that psychosocial stress may increase risk for
psychosis, especially in the case of cumulative exposure. A heuristically useful framework to …

This review summarizes our current understanding of catechol-o-methyltransferase (COMT)
and how it relates to brain function and schizophrenia. We begin by considering the COMT …

Genetic variation in catechol-O-methyltransferase (COMT), encoding an enzyme critical for
prefrontal dopamine flux, has been studied extensively using both behavioral and …