Biotechnological approaches for the production of camptothecin

A Banadka, SW Narasimha, VS Dandin… - Applied Microbiology …, 2024 - Springer
Camptothecin (CPT), an indole alkaloid popular for its anticancer property, is considered the
third most promising drug after taxol and famous alkaloids from Vinca for the treatment of …

Genomic and transcriptomic analysis of camptothecin producing novel fungal endophyte: Alternaria burnsii NCIM 1409

S Natarajan, B Pucker, S Srivastava - Scientific Reports, 2023 - nature.com
Camptothecin is an important anticancer alkaloid produced by particular plant species. No
suitable synthetic route has been established for camptothecin production yet, imposing a …

Optimisation of enzyme‐assisted extraction of camptothecin from Nothapodytes nimmoniana and its characterisation

DM Patil, BS Hunasagi, AV Raghu… - Phytochemical …, 2024 - Wiley Online Library
Introduction Efficient extraction of camptothecin (CPT), an anticancer agent from the
commercial source Nothapodytes nimmoniana (J. Graham) Mabb in India, is of paramount …

Phytochemical profiling of Nothapodytes nimmoniana to understand camptothecin biosynthesis using tandem mass spectrometry

RC Godbole, AA Pable, S Singh, VT Barvkar - South African Journal of …, 2023 - Elsevier
Nothapodytes nimmoniana is a medicinally important plant producing camptothecin (CPT)
which is a well-known anti-cancer drug. Its analogues viz. topotecan and irinotecan are …

Endangered medicinal plants of western ghats: A review

J Malavika - Kongunadu Research Journal, 2023 - krjournal.com
India houses about more than a thousand known medicinal plant species. Traditional Indian
medicine, also known as Ayurveda, relies heavily on the use of medicinal plants for treating …

Assessment of threatened arborous species in the Nilgiri Biosphere Reserve, Southern Western Ghats, India

V Sakkamuthu, A Sarvalingam, K Thangadurai - 2024 - researchsquare.com
Abstract The Western Ghats are the world's second-most significant refuge for species at
risk, particularly in the Nilgiri, a part of the Southern Western Ghats (SWG) region that is one …

Medicinal Chemistry, Pharmacodynamics, and Pharmacokinetics of Camptothecin and Its Derivatives in Clinical Chemotherapeutics

TP Ijinu, P Sasikumar, V Aparna… - Natural Products and …, 2023 - taylorfrancis.com
Camptothecin is a planar pentacyclic alkaloid containing a pyrrolo (3, 4-β) quinoline and an
α-hydroxy lactone, discovered in the early 1960s from the stem wood of Camptotheca …

Vandhanam Aparna, Sreejith Pongillyathundiyil Sasidharan, Vipin Mohan Dan, Farkhodjon Tukhtaev, Varughese George, and Palpu Pushpangadan

TP Ijinu, P Sasikumar - api.taylorfrancis.com
Camptothecin (CPT) is a tryptophan-derived quinoline alkaloid with a unique planar
pentacyclic structure [1–3], which was originally obtained from the stem wood and bark of …