Molecular targets and anticancer activity of quinoline–chalcone hybrids: Literature review

MFA Mohamed, GEDA Abuo-Rahma - RSC advances, 2020 - pubs.rsc.org
α, β-Unsaturated chalcone moieties and quinoline scaffolds play an important role in
medicinal chemistry, especially in the identification and development of potential anticancer …

Quinoline-based antimalarial hybrid compounds

S Vandekerckhove, M D'hooghe - Bioorganic & medicinal chemistry, 2015 - Elsevier
Quinoline-containing compounds, such as quinine and chloroquine, have a long-standing
history as potent antimalarial agents. However, the increasing resistance of the Plasmodium …

Anticancer activities of novel chalcone and bis-chalcone derivatives

A Modzelewska, C Pettit, G Achanta… - Bioorganic & medicinal …, 2006 - Elsevier
A series of novel chalcones and bis-chalcones containing boronic acid moieties has been
synthesized and evaluated for antitumor activity against the human breast cancer MDA-MB …

Dietary chalcones with chemopreventive and chemotherapeutic potential

B Orlikova, D Tasdemir, F Golais, M Dicato… - Genes & nutrition, 2011 - Springer
Chalcones are absorbed in the daily diet and appear to be promising cancer
chemopreventive agents. Chalcones represent an important group of the polyphenolic …

Novel thiophene Chalcones-Coumarin as acetylcholinesterase inhibitors: Design, synthesis, biological evaluation, molecular docking, ADMET prediction and …

AH Hasan, S Murugesan, SI Amran, S Chander… - Bioorganic …, 2022 - Elsevier
A series of around eight novel chalcone based coumarin derivatives (23a-h) was designed,
subjected to in-silico ADMET prediction, synthesized, characterized by IR, NMR, Mass …

Synthetic chalcones as potential anti-inflammatory and cancer chemopreventive agents

SJ Won, CT Liu, LT Tsao, JR Weng, HH Ko… - European journal of …, 2005 - Elsevier
In an effort to develop potent anti-inflammatory and cancer chemopreventive agents, a
series of chalcones were prepared by Claisen–Schmidt condensation of appropriate …

Emerging role of Garcinol, the antioxidant chalcone from Garcinia indica Choisy and its synthetic analogs

S Padhye, A Ahmad, N Oswal, FH Sarkar - Journal of hematology & …, 2009 - Springer
Garcinol, harvested from Garcinia indica, has traditionally been used in tropical regions and
appreciated for centuries; however its biological properties are only beginning to be …

Synthesis and antihyperglycemic activity of chalcone based aryloxypropanolamines

M Satyanarayana, P Tiwari, BK Tripathi… - Bioorganic & medicinal …, 2004 - Elsevier
A series of aryloxypropanolamines (5a–r) of different chalcones (3a–e) were synthesized
and evaluated for antihyperglycemic activity in sucrose loaded (SLM) and streptozotocin …

Synthesis of novel quinoline–based 4, 5–dihydro–1H–pyrazoles as potential anticancer, antifungal, antibacterial and antiprotozoal agents

J Ramírez–Prada, SM Robledo, ID Vélez… - European journal of …, 2017 - Elsevier
A new series of N–substituted 2–pyrazolines 9a–f, 10a–f, 11a–f, 12a–f and 13a–f were
obtained from the cyclocondensation reaction of [(7–chloroquinolin–4–yl) amino] chalcones …

Prediction of breast cancer using volatile biomarkers in the breath

M Phillips, RN Cataneo, BA Ditkoff, P Fisher… - Breast cancer research …, 2006 - Springer
We evaluated a breath test for volatile organic compounds (VOCs) as a predictor of breast
cancer. Breath VOCs were assayed in 51 asymptomatic women with abnormal …