[HTML][HTML] Missing data in clinical research: a tutorial on multiple imputation

PC Austin, IR White, DS Lee, S van Buuren - Canadian Journal of …, 2021 - Elsevier
Missing data is a common occurrence in clinical research. Missing data occurs when the
value of the variables of interest are not measured or recorded for all subjects in the sample …

[HTML][HTML] Trial of an intervention to improve acute heart failure outcomes

DS Lee, SE Straus, ME Farkouh… - … England Journal of …, 2023 - Mass Medical Soc
Background Patients with acute heart failure are frequently or systematically hospitalized,
often because the risk of adverse events is uncertain and the options for rapid follow-up are …

Machine learning compared with conventional statistical models for predicting myocardial infarction readmission and mortality: a systematic review

SM Cho, PC Austin, HJ Ross, H Abdel-Qadir… - Canadian Journal of …, 2021 - Elsevier
Background Machine learning (ML) methods are increasingly used in addition to
conventional statistical modelling (CSM) for predicting readmission and mortality in patients …

Machine learning vs. conventional statistical models for predicting heart failure readmission and mortality

S Shin, PC Austin, HJ Ross, H Abdel‐Qadir… - ESC heart …, 2021 - Wiley Online Library
Aims This study aimed to review the performance of machine learning (ML) methods
compared with conventional statistical models (CSMs) for predicting readmission and …

Two way workable microchanneled hydrogel suture to diagnose, treat and monitor the infarcted heart

F Xue, S Zhao, H Tian, H Qin, X Li, Z Jian, J Du… - Nature …, 2024 - nature.com
During myocardial infarction, microcirculation disturbance in the ischemic area can cause
necrosis and formation of fibrotic tissue, potentially leading to malignant arrhythmia and …

Using fractional polynomials and restricted cubic splines to model non‐proportional hazards or time‐varying covariate effects in the Cox regression model

PC Austin, J Fang, DS Lee - Statistics in medicine, 2022 - Wiley Online Library
The Cox proportional hazards model is used extensively in clinical and epidemiological
research. A key assumption of this model is that of proportional hazards. A variable satisfies …

[HTML][HTML] Association of left ventricular ejection fraction with mortality and hospitalizations

P Angaran, P Dorian, ACT Ha… - Journal of the American …, 2020 - Elsevier
Background Although echocardiography is widely used to measure left ventricular ejection
fraction (LVEF), its prognostic value has not been demonstrated in a broad range of patients …

Hospital at home as a treatment strategy for worsening heart failure

HB Haywood, GC Fonarow, MS Khan… - Circulation: Heart …, 2023 - Am Heart Assoc
Hospital at home (HaH) is an innovative care model that may be particularly suited for heart
failure (HF). Outpatient visits and inpatient care have been the 2 traditional settings for HF …

Use of machine learning to develop a risk-stratification tool for emergency department patients with acute heart failure

DR Sax, DG Mark, J Huang, O Sofrygin, JS Rana… - Annals of Emergency …, 2021 - Elsevier
Study objective We use variables from a recently derived acute heart failure risk-stratification
rule (STRATIFY) as a basis to develop and optimize risk prediction using additional patient …

Association of neighbourhood‐level material deprivation with adverse outcomes and processes of care among patients with heart failure in a single‐payer healthcare …

D Bobrowski, A Dorovenis… - European Journal of …, 2023 - Wiley Online Library
Aim We studied the association between neighbourhood material deprivation, a metric
estimating inability to attain basic material needs, with outcomes and processes of care …