Cancer development and its response to therapy are regulated by inflammation, which
either promotes or suppresses tumor progression, potentially displaying opposing effects on …

The ribosome has recently transitioned from being viewed as a passive, indiscriminate
machine to a more dynamic macromolecular complex with specialized roles in the cell …

Although ribosomal proteins are known for playing an essential role in ribosome assembly
and protein translation, their ribosome-independent functions have also been greatly …

Reduced glomerular filtration rate defines chronic kidney disease and is associated with
cardiovascular and all-cause mortality. We conducted a meta-analysis of genome-wide …

Small nucleolar RNAs (snoRNAs) are short non-protein-coding RNAs with a long-
recognized role in tuning ribosomal and spliceosomal function by guiding ribose methylation …

Members of the GroEL/HSP60 protein family have been studied for many years because of
their critical roles as ATP-dependent molecular chaperones, so it might come as a surprise …

Historically, the ribosome has been viewed as a complex ribozyme with constitutive rather
than intrinsic regulatory capacity in mRNA translation. However, emerging studies reveal …

Ribosomal protein genes are among the most highly expressed genes in most cell types.
Their products are generally essential for ribosome synthesis, which is the cornerstone for …

Regulation of mRNA translation offers the opportunity to diversify the expression and
abundance of proteins made from individual gene products in cells, tissues and organisms …

Innate immune responses combat infectious microorganisms by inducing inflammatory
responses, antimicrobial pathways and adaptive immunity. Multiple genes within each of …