[HTML][HTML] Peptide–drug conjugates (PDCs): a novel trend of research and development on targeted therapy, hype or hope?
C Fu, L Yu, Y Miao, X Liu, Z Yu, M Wei - Acta Pharmaceutica Sinica B, 2023 - Elsevier
Peptide–drug conjugates (PDCs) are the next generation of targeted therapeutics drug after
antibody–drug conjugates (ADCs), with the core benefits of enhanced cellular permeability …
antibody–drug conjugates (ADCs), with the core benefits of enhanced cellular permeability …
Peptide receptor radionuclide therapy
J Hofland, T Brabander, FA Verburg… - The Journal of …, 2022 - academic.oup.com
The concept of using a targeting molecule labeled with a diagnostic radionuclide for using
positron emission tomography or single photon emission computed tomography imaging …
positron emission tomography or single photon emission computed tomography imaging …
Radiomics and Artificial Intelligence in Radiotheranostics: a review of applications for Radioligands Targeting somatostatin receptors and prostate-specific membrane …
E Yazdani, P Geramifar, N Karamzade-Ziarati… - Diagnostics, 2024 - mdpi.com
Radiotheranostics refers to the pairing of radioactive imaging biomarkers with radioactive
therapeutic compounds that deliver ionizing radiation. Given the introduction of very …
therapeutic compounds that deliver ionizing radiation. Given the introduction of very …
Interim analysis of a prospective validation of 2 blood-based genomic assessments (PPQ and NETest) to determine the clinical efficacy of 177Lu-DOTATATE in …
Reliable biomarkers for neuroendocrine tumor (NET) management during peptide receptor
radionuclide therapy (PRRT) are lacking. We validated the role of 2 circulating biomarkers …
radionuclide therapy (PRRT) are lacking. We validated the role of 2 circulating biomarkers …
Relationships between uptake of [68Ga]Ga-DOTA-TATE and absorbed dose in [177Lu]Lu-DOTA-TATE therapy
A Stenvall, J Gustafsson, E Larsson, D Roth… - EJNMMI research, 2022 - Springer
Abstract Background Somatostatin receptor 68Ga PET imaging is standard for evaluation of
a patient's suitability for 177Lu peptide receptor radionuclide therapy of neuroendocrine …
a patient's suitability for 177Lu peptide receptor radionuclide therapy of neuroendocrine …
New insights in PRRT: lessons from 2021
G Puliani, A Chiefari, M Mormando… - Frontiers in …, 2022 - frontiersin.org
Peptide receptor radionuclide therapy (PRRT) using radiolabeled somatostatin analogs has
been used for over two decades for the treatment of well-differentiated neuroendocrine …
been used for over two decades for the treatment of well-differentiated neuroendocrine …
Potential value of pre-and post-therapy [68Ga] Ga-DOTA-TATE PET/CT in the prognosis of response to PRRT in disseminated neuroendocrine tumors
M Opalińska, K Morawiec-Sławek… - Frontiers in …, 2022 - frontiersin.org
Background Peptide receptor radionuclide therapy (PRRT) is one of the most effective
therapeutic options for the treatment of metastatic, well-differentiated neuroendocrine tumors …
therapeutic options for the treatment of metastatic, well-differentiated neuroendocrine tumors …
Prognostic implications of PET-derived tumor volume and uptake in patients with neuroendocrine tumors
M Weber, T Telli, D Kersting, R Seifert - Cancers, 2023 - mdpi.com
Simple Summary The monitoring of disease in patients with neuroendocrine tumors is
challenging and requires specialized imaging techniques. To address these quests …
challenging and requires specialized imaging techniques. To address these quests …
Predictive and prognostic role of pre-therapy and interim 68Ga-DOTATOC PET/CT parameters in metastatic advanced neuroendocrine tumor patients treated with …
R Durmo, A Filice, F Fioroni, V Cervati, D Finocchiaro… - Cancers, 2022 - mdpi.com
Simple Summary Although a significant improvement has been achieved in the
management of metastatic neuroendocrine tumor (NET), disease progression is observed in …
management of metastatic neuroendocrine tumor (NET), disease progression is observed in …
Quantitative SPECT/CT for dosimetry of peptide receptor radionuclide therapy
J Kennedy, A Chicheportiche, Z Keidar - Seminars in nuclear medicine, 2022 - Elsevier
Neuroendocrine tumors (NETs) are uncommon malignancies of increasing incidence and
prevalence. As these slow growing tumors usually overexpress somatostatin receptors …
prevalence. As these slow growing tumors usually overexpress somatostatin receptors …