The accurate regulation of the microenvironment within the nervous system is one of the key
features characterizing complex organisms. To this end, neural tissue has to be physically …

Molecular genetic approaches in small model organisms like Drosophila have helped to
elucidate fundamental principles of neuronal cell biology. Much less is understood about …

Spontaneous Ca2+ transients of neural cells is a hallmark of the developing nervous
system. It is widely accepted that chemical signals, like neurotransmitters, contribute to …

The sleep-wake cycle stands as an integrative process essential for sustaining optimal brain
function and, either directly or indirectly, overall body health, encompassing metabolic and …

Heparan sulfate proteoglycans (HSPGs) form essential components of the extracellular
matrix (ECM) and basement membrane (BM) and have both structural and signaling roles …

The Drosophila nervous system comprises a small number of well characterized glial cell
classes. The outer surface of the central nervous system (CNS) is protected by a glial …

Background Postinduction hypotension caused by propofol remains a non-negligible
problem for anesthesiologists, and is especially severe in chronic hypertensive patients with …

Glia are essential to protecting and enabling nervous system function and a key glial
function is the formation of the glial sheath around peripheral axons. Each peripheral nerve …

Intracellular Ca2+-signaling in astrocytes is instrumental for their brain “housekeeping” role
and astroglial control of synaptic plasticity. An important source for elevating the cytosolic …

The blood–brain barrier (BBB) represents a crucial interface between the circulatory system
and the brain. In Drosophila melanogaster, the BBB is composed of perineurial and …