Background The human endometrium is a highly dynamic tissue whose function is mainly
regulated by the ovarian steroid hormones estradiol and progesterone. The serum levels of …

Epigenetic mechanisms can alter gene expression without a change in the nucleotide
sequence and are increasingly recognized as important mechanisms that can generate …

In seasonal environments, timing of reproduction is a trait with important fitness
consequences, but we know little about the molecular mechanisms that underlie the …

Animals have evolved diverse seasonal variations in physiology and reproduction to
accommodate yearly changes in environmental and climatic conditions. These changes in …

Background Ovulation rate and litter size are important reproductive traits in sheep with high
economic value. Recent work has revealed a potential link between DNA methylation and …

Circadian rhythms are evolutionarily programmed biological rhythms that are primarily
entrained by the light cycle. Disruption of circadian rhythms is an important risk factor for …

Biological rhythms are pervasive in nature, yet our understanding of the molecular
mechanisms that govern timing is far from complete. The rapidly emerging research focus on …

Seasonal rhythms in reproduction are conserved across nature and optimize the timing of
breeding to environmental conditions favorable for offspring and parent survival. The …

Temperate zone animals exhibit seasonal variation in multiple endocrine systems. In most
cases, peripheral organs display robust switches in tissue involution and recrudescence in …

Seasonal breeders predominantly use photoperiod as the predictable environmental cue to
time their reproduction. Terai tree frogs are long-day seasonal breeders, but the molecular …