Prophages provide a rich source of antiphage defense systems

PH Patel, KL Maxwell - Current Opinion in Microbiology, 2023 - Elsevier
Temperate phages are pervasive in nature, existing within bacterial cells in a form known as
prophages. In this state, survival of the phage is intricately tied to the survival of the bacterial …

Bacteriophages as drivers of bacterial virulence and their potential for biotechnological exploitation

K Schroven, A Aertsen, R Lavigne - FEMS microbiology reviews, 2021 - academic.oup.com
Bacteria-infecting viruses (phages) and their hosts maintain an ancient and complex
relationship. Bacterial predation by lytic phages drives an ongoing phage-host arms race …

[HTML][HTML] Prophages encode phage-defense systems with cognate self-immunity

SV Owen, N Wenner, CL Dulberger, EV Rodwell… - Cell host & …, 2021 - cell.com
Temperate phages are pervasive in bacterial genomes, existing as vertically inherited
islands termed prophages. Prophages are vulnerable to predation of their host bacterium by …

Moisture modulates soil reservoirs of active DNA and RNA viruses

R Wu, MR Davison, Y Gao, CD Nicora… - Communications …, 2021 - nature.com
Soil is known to harbor viruses, but the majority are uncharacterized and their responses to
environmental changes are unknown. Here, we used a multi-omics approach …

[HTML][HTML] Infant gut DNA bacteriophage strain persistence during the first 3 years of life

YC Lou, LX Chen, AL Borges, J West-Roberts… - Cell Host & Microbe, 2024 - cell.com
Bacteriophages are key components of gut microbiomes, yet the phage colonization process
in the infant gut remains uncertain. Here, we establish a large phage sequence database …

The role of temperate phages in bacterial pathogenicity

VS Gummalla, Y Zhang, YT Liao, VCH Wu - Microorganisms, 2023 - mdpi.com
Bacteriophages are viruses that infect bacteria and archaea and are classified as virulent or
temperate phages based on their life cycles. A temperate phage, also known as a lysogenic …

The human gut virome: composition, colonization, interactions, and impacts on human health

E Pargin, MJ Roach, A Skye, B Papudeshi… - Frontiers in …, 2023 - frontiersin.org
The gut virome is an incredibly complex part of the gut ecosystem. Gut viruses play a role in
many disease states, but it is unknown to what extent the gut virome impacts everyday …

Spontaneous Prophage Induction Contributes to the Production of Membrane Vesicles by the Gram-Positive Bacterium Lacticaseibacillus casei BL23

D da Silva Barreira, P Lapaquette, J Novion Ducassou… - MBio, 2022 - Am Soc Microbiol
The formation of membrane vesicles (MVs) by Gram-positive bacteria has gained increasing
attention over the last decade. Recently, models of vesicle formation have been proposed …

Dairy lactococcal and streptococcal phage–host interactions: an industrial perspective in an evolving phage landscape

DA Romero, D Magill, A Millen… - FEMS Microbiology …, 2020 - academic.oup.com
Almost a century has elapsed since the discovery of bacteriophages (phages), and 85 years
have passed since the emergence of evidence that phages can infect starter cultures …

The enemy of my enemy: new insights regarding bacteriophage–mammalian cell interactions

K Bodner, AL Melkonian, MW Covert - Trends in Microbiology, 2021 - cell.com
Bacteriophages (phages) are the most abundant biological entity in the human body, but
until recently the role that phages play in human health was not well characterized. Although …