Effects of short‐term mild hypercapnia during head‐down tilt on intracranial pressure and ocular structures in healthy human subjects
Many astronauts experience ocular structural and functional changes during long‐duration
spaceflight, including choroidal folds, optic disc edema, globe flattening, optic nerve sheath …
spaceflight, including choroidal folds, optic disc edema, globe flattening, optic nerve sheath …
Measuring the human ventilatory and cerebral blood flow response to CO2: a technical consideration for the end-tidal-to-arterial gas gradient
MM Tymko, RL Hoiland, T Kuca… - Journal of Applied …, 2016 - journals.physiology.org
Our aim was to quantify the end-tidal-to-arterial gas gradients for O2 (PET-PaO2) and CO2
(Pa-PETCO2) during a CO2 reactivity test to determine their influence on the …
(Pa-PETCO2) during a CO2 reactivity test to determine their influence on the …
Cerebrovascular reactivity and cerebral autoregulation are improved in the supine posture compared to upright in healthy men and women
Cerebrovascular reactivity and cerebral autoregulation are two major mechanisms that
regulate cerebral blood flow. Both mechanisms are typically assessed in either supine or …
regulate cerebral blood flow. Both mechanisms are typically assessed in either supine or …
Effects of short-term exposure to head-down tilt on cerebral hemodynamics: a prospective evaluation of a spaceflight analog using phase-contrast MRI
K Marshall-Goebel, K Ambarki… - Journal of Applied …, 2016 - journals.physiology.org
Alterations in cerebral hemodynamics in microgravity are hypothesized to occur during
spaceflight and could be linked to the Visual Impairment and Intracranial Pressure …
spaceflight and could be linked to the Visual Impairment and Intracranial Pressure …
Dynamic cerebral autoregulation and cerebrovascular carbon dioxide reactivity in middle and posterior cerebral arteries in young endurance-trained women
L Labrecque, A Drapeau, K Rahimaly… - Journal of Applied …, 2021 - journals.physiology.org
The integrated responses regulating cerebral blood flow are understudied in women,
particularly in relation to potential regional differences. In this study, we compared dynamic …
particularly in relation to potential regional differences. In this study, we compared dynamic …
Unchanged cerebrovascular CO2 reactivity and hypercapnic ventilatory response during strict head‐down tilt bed rest in a mild hypercapnic environment
Key points Carbon dioxide levels are mildly elevated on the International Space Station and
it is unknown whether this chronic exposure causes physiological changes to astronauts …
it is unknown whether this chronic exposure causes physiological changes to astronauts …
Effects of− 10° and− 30° head-down tilt on cerebral blood velocity, dynamic cerebral autoregulation, and noninvasively estimated intracranial pressure
T Kato, T Kurazumi, T Konishi… - Journal of Applied …, 2022 - journals.physiology.org
Steady-state cerebral blood flow (CBF) and dynamic cerebral autoregulation are reportedly
maintained during− 10° head-down tilt (HDT) despite slight increases in intracranial …
maintained during− 10° head-down tilt (HDT) despite slight increases in intracranial …
Quantifying cerebrovascular reactivity in anterior and posterior cerebral circulations during voluntary breath holding
CD Bruce, CD Steinback, UV Chauhan… - Experimental …, 2016 - Wiley Online Library
New Findings What is the central question of this study? We developed and validated a
'stimulus index'(SI; ratio of end‐tidal partial pressures of CO2 and O2) method to quantify …
'stimulus index'(SI; ratio of end‐tidal partial pressures of CO2 and O2) method to quantify …
Protocol-dependence of middle cerebral artery dilation to modest hypercapnia
There is a need for improved understanding of how different cerebrovascular reactivity
(CVR) protocols affect vascular cross-sectional area (CSA) to reduce error in CVR …
(CVR) protocols affect vascular cross-sectional area (CSA) to reduce error in CVR …
The effects of superimposed tilt and lower body negative pressure on anterior and posterior cerebral circulations
Steady‐state tilt has no effect on cerebrovascular reactivity to increases in the partial
pressure of end‐tidal carbon dioxide (PETCO 2). However, the anterior and posterior …
pressure of end‐tidal carbon dioxide (PETCO 2). However, the anterior and posterior …