The alcohol flushing response: an unrecognized risk factor for esophageal cancer from alcohol consumption
PJ Brooks, MA Enoch, D Goldman, TK Li… - PLoS …, 2009 - journals.plos.org
The Alcohol Flushing Response: An Unrecognized Risk Factor for Esophageal Cancer from
Alcohol Consumption | PLOS Medicine Skip to main content Advertisement PLOS Medicine …
Alcohol Consumption | PLOS Medicine Skip to main content Advertisement PLOS Medicine …
Effect of the allelic variants of aldehyde dehydrogenase ALDH2*2 and alcohol dehydrogenase ADH1B*2on blood acetaldehyde concentrations
GS Peng, SJ Yin - Human genomics, 2009 - Springer
Alcoholism is a complex behavioural disorder. Molecular genetics studies have identified
numerous candidate genes associated with alcoholism. It is crucial to verify the disease …
numerous candidate genes associated with alcoholism. It is crucial to verify the disease …
Strong protective effect of the aldehyde dehydrogenase gene (ALDH2) 504lys (*2) allele against alcoholism and alcohol-induced medical diseases in Asians
Alcohol is oxidized to acetaldehyde, which in turn is oxidized to acetate. The aldehyde
dehydrogenase 2 gene (ALDH2) is the most important gene responsible for acetaldehyde …
dehydrogenase 2 gene (ALDH2) is the most important gene responsible for acetaldehyde …
Strong association of the alcohol dehydrogenase 1B gene (ADH1B) with alcohol dependence and alcohol-induced medical diseases
BACKGROUND: The alcohol dehydrogenase 1B gene (ADH1B) is hypothesized to affect
predisposition to alcohol dependence (AD) and abuse. A variant of the ADH1B gene …
predisposition to alcohol dependence (AD) and abuse. A variant of the ADH1B gene …
The ADH1B Arg47His polymorphism in East Asian populations and expansion of rice domestication in history
Y Peng, H Shi, X Qi, C Xiao, H Zhong, RZ Ma… - BMC evolutionary …, 2010 - Springer
Background The emergence of agriculture about 10,000 years ago marks a dramatic
change in human evolutionary history. The diet shift in agriculture societies might have a …
change in human evolutionary history. The diet shift in agriculture societies might have a …
Extended genetic effects of ADH cluster genes on the risk of alcohol dependence: from GWAS to replication
BL Park, JW Kim, HS Cheong, LH Kim, BC Lee… - Human genetics, 2013 - Springer
Alcohol dependence (AD) is a multifactorial and polygenic disorder involving complex gene-
to-gene and gene-to-environment interactions. Several genome-wide association studies …
to-gene and gene-to-environment interactions. Several genome-wide association studies …
Dominance of the inactive Asian variant over activity and protein contents of mitochondrial aldehyde dehydrogenase 2 in human liver
CL Lai, CT Yao, GY Chau, LF Yang… - Alcoholism: Clinical …, 2014 - Wiley Online Library
Background It has been well documented that a variant allele of mitochondrial aldehyde
dehydrogenase 2 (ALDH 2), ALDH 2* 2, commonly occurs in East Asians but rarely in other …
dehydrogenase 2 (ALDH 2), ALDH 2* 2, commonly occurs in East Asians but rarely in other …
Polymorphism of ethanol-metabolism genes and alcoholism: correlation of allelic variations with the pharmacokinetic and pharmacodynamic consequences
YC Chen, GS Peng, MF Wang, TP Tsao… - Chemico-biological …, 2009 - Elsevier
Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) are the principal
enzymes responsible for metabolism of ethanol. Both ADH and ALDH exhibit genetic …
enzymes responsible for metabolism of ethanol. Both ADH and ALDH exhibit genetic …
Alcohol addiction: a molecular biology perspective
G Ferraguti, E Pascale… - Current medicinal …, 2015 - ingentaconnect.com
Alcohol misuse represents worldwide an important risk factor for death and disability.
Excessive alcohol consumption is widely diffused in different ethnicities and alcohol use is …
Excessive alcohol consumption is widely diffused in different ethnicities and alcohol use is …
Genetic Polymorphisms of Alcohol Dehydrogenase‐1 B and Aldehyde Dehydrogenase‐2 and Liver Cirrhosis, Chronic Calcific Pancreatitis, Diabetes Mellitus, and …
A Yokoyama, T Mizukami, T Matsui… - Alcoholism: Clinical …, 2013 - Wiley Online Library
Background The presence of the less‐active form of alcohol dehydrogenase‐1B encoded by
ADH1B* 1/* 1 (vs.* 2 allele) and active form of aldehyde dehydrogenase‐2 (ALDH2) …
ADH1B* 1/* 1 (vs.* 2 allele) and active form of aldehyde dehydrogenase‐2 (ALDH2) …