The extracellular matrix (ECM) is a network of different proteins and proteoglycans that
controls differentiation, migration, repair, survival, and development, and it seems that its …

Matrix metalloproteinases (MMPs) are identifiable members of proteolytic enzymes that can
degrade a wide range of proteins in the extracellular matrix (ECM). MMPs can be …

Microbiota contribute to the induction of type 2 diabetes by high-fat/high-sugar (HFHS) diet,
but which organs/pathways are impacted by microbiota remain unknown. Using multiorgan …

Matrix metalloproteinases (MMPs) are a family of proteins involved in a range of
pathologies. Given that MMP broad-spectrum inhibition is associated with severe adverse …

Arterial stiffening is a consequence of aging and a cholesterol-independent risk factor for
cardiovascular disease (CVD). Arterial stiffening and CVD show a sex bias, with men more …

Abstract Background Matrix metalloproteinase 12 (MMP12) is a macrophage-secreted
protein that is massively upregulated as a pro-inflammatory factor in metabolic and vascular …

Irreversible tissue recession in chronic inflammatory diseases is associated with
dysregulated immune activation and production of tissue degradative enzymes. In this study …

The ratio of free fatty acid (FFA) turnover decreases significantly with the expansion of white
adipose tissue. Adipose tissue and dietary saturated fatty acid levels significantly correlate …

Oral lichen planus (OLP) is a chronic inflammatory disorder featured with T lymphocytes
infiltration and epithelial basement membrane breakdown. Although matrix …

Background The salivary glands of Lucilia sericata are the first organs to express specific
endopeptidase enzymes. These enzymes play a central role in wound healing, and they …