Schizophrenia and other psychotic disorders are highly debilitating psychiatric conditions
that lack a clear etiology and exhibit polygenic inheritance underlain by pleiotropic genes …

Schizophrenia is a severe psychiatric disorder with a complex array of signs and symptoms
that causes very significant disability in young people. While schizophrenia has a strong …

Recent studies suggest that genetic and environmental factors do not account for all the
schizophrenia risk, and epigenetics also has a role in disease susceptibility. DNA …

Schizophrenia is a neuropsychiatric disorder characterized by dissociation of thoughts, idea,
identity, and emotions. It has no central pathophysiological mechanism and precise …

A significant proportion of the global burden of disease can be attributed to mental illness.
Despite important advances in identifying risk factors for mental health conditions, the …

DNA methylation is a fundamental epigenetic modification in the human genome; pivotal in
development, genomic imprinting, X inactivation, chromosome stability, gene expression …

Objectives Aberrant DNA methylation and gene expression have been reported in
postmortem brain tissues of psychotic patients, but until now there has been no systematic …

Background Increasing evidence suggests the involvement of epigenetic processes in the
development of schizophrenia and bipolar disorder, and recent reviews have focused on …

DNA methylation has been an important area of research in the study of molecular
mechanism to psychiatric disorders. Recent evidence has suggested that abnormalities in …

The newly evolved circuits in layer III of primate dorsolateral prefrontal cortex (dlPFC)
generate the neural representations that subserve working memory. These circuits are …