Long runs of homozygosity (ROH) arise when identical haplotypes are inherited from each
parent and thus a long tract of genotypes is homozygous. Cousin marriage or inbreeding …

This review presents a broader approach to the implementation and study of runs of
homozygosity (ROH) in animal populations, focusing on identifying and characterizing ROH …

Behavioral genetics in dogs has focused on modern breeds, which are isolated subgroups
with distinctive physical and, purportedly, behavioral characteristics. We interrogated breed …

General cognitive function is a prominent and relatively stable human trait that is associated
with many important life outcomes. We combine cognitive and genetic data from the …

Reduced glomerular filtration rate defines chronic kidney disease and is associated with
cardiovascular and all-cause mortality. We conducted a meta-analysis of genome-wide …

Background PLINK is probably the most used program for analyzing SNP genotypes and
runs of homozygosity (ROH), both in human and in animal populations. The last decade …

Elevated serum urate levels cause gout and correlate with cardiometabolic diseases via
poorly understood mechanisms. We performed a trans-ancestry genome-wide association …

We extend the scope of European palaeogenomics by sequencing the genomes of Late
Upper Palaeolithic (13,300 years old, 1.4-fold coverage) and Mesolithic (9,700 years old …

The sustainability of malaria control in Africa is threatened by the rise of insecticide
resistance in Anopheles mosquitoes that transmit the disease 1. To gain a deeper …

The use of omic modalities to dissect the molecular underpinnings of common diseases and
traits is becoming increasingly common. But multi-omic traits can be genetically predicted …