Brain–heart interaction after acute ischemic stroke

D Battaglini, C Robba, A Lopes da Silva… - Critical Care, 2020 - Springer
Early detection of cardiovascular dysfunctions directly caused by acute ischemic stroke (AIS)
has become paramount. Researchers now generally agree on the existence of a …

Creation and application of virtual patient cohorts of heart models

SA Niederer, Y Aboelkassem… - … of the Royal …, 2020 - royalsocietypublishing.org
Patient-specific cardiac models are now being used to guide therapies. The increased use
of patient-specific cardiac simulations in clinical care will give rise to the development of …

Polygonal surface processing and mesh generation tools for the numerical simulation of the cardiac function

M Fedele, A Quarteroni - International Journal for Numerical …, 2021 - Wiley Online Library
In order to simulate the cardiac function for a patient‐specific geometry, the generation of the
computational mesh is crucially important. In practice, the input is typically a set of …

Demonstration of patient-specific simulations to assess left atrial appendage thrombogenesis risk

M García-Villalba, L Rossini, A Gonzalo… - Frontiers in …, 2021 - frontiersin.org
Atrial fibrillation (AF) alters left atrial (LA) hemodynamics, which can lead to thrombosis in
the left atrial appendage (LAA), systemic embolism and stroke. A personalized risk …

Hemodynamics of the heart's left atrium based on a variational multiscale-LES numerical method

A Zingaro, F Menghini, A Quarteroni - European Journal of Mechanics-B …, 2021 - Elsevier
In this paper, we investigate the haemodynamics of a left atrium (LA) by proposing a
computational model suitable to provide physically meaningful fluid dynamics indications …

[HTML][HTML] A comprehensive comparison of various patient-specific CFD models of the left atrium for atrial fibrillation patients

J Dueñas-Pamplona, JG García… - Computers in Biology …, 2021 - Elsevier
Background Recently, advances in medical imaging, segmentation techniques, and high-
performance computing have supported the use of patient-specific computational fluid …

Impact of atrial fibrillation on left atrium haemodynamics: A computational fluid dynamics study

M Corti, A Zingaro, AM Quarteroni - Computers in Biology and Medicine, 2022 - Elsevier
We analyse the haemodynamics of the left atrium, highlighting differences between healthy
individuals and patients affected by atrial fibrillation. The computational study is based on …

[HTML][HTML] An electromechanics-driven fluid dynamics model for the simulation of the whole human heart

A Zingaro, M Bucelli, R Piersanti, F Regazzoni… - Journal of …, 2024 - Elsevier
We introduce a multiphysics and geometric multiscale computational model, suitable to
describe the hemodynamics of the whole human heart, driven by a four-chamber …

A geometric multiscale model for the numerical simulation of blood flow in the human left heart

A Zingaro, I Fumagalli, L Dede, M Fedele… - arXiv preprint arXiv …, 2021 - arxiv.org
We present a new computational model for the numerical simulation of blood flow in the
human left heart. To this aim, we use the Navier-Stokes equations in an Arbitrary Lagrangian …

Sensitivity analysis of in silico fluid simulations to predict thrombus formation after left atrial appendage occlusion

J Mill, V Agudelo, AL Olivares, MI Pons, E Silva… - Mathematics, 2021 - mdpi.com
Atrial fibrillation (AF) is nowadays the most common human arrhythmia and it is considered
a marker of an increased risk of embolic stroke. It is known that 99% of AF-related thrombi …