Epidemiological evidence suggests that flavonoids may play an important role in the
decreased risk of chronic diseases associated with a diet rich in plant-derived foods …

Infections with protozoan parasites are a major cause of disease and mortality in many
tropical countries of the world. Diseases caused by species of the genera Trypanosoma …

Trypanosomiasis and leishmaniasis are important parasitic diseases affecting millions of
people in Africa, Asia, and South America. In a previous study, we identified several …

Current knowledge of the biochemistry of Trypanosoma cruzi has led to the development of
new drugs and the understanding of their mode of action. Some trypanocidal drugs such as …

Pain due to chronic conditions is a frequent and insufficiently addressed problem. Current
drug options for pain management (either in cases of chronic inflammatory conditions or …

Flavonoids are metabolites widely distributed in plants and commonly present in foods, such
as fruits and vegetables. Pectolinarin, which belongs to the flavone subclass, has attracted …

Covering: 1995 to 2010 Here, we review studies that have investigated the activity of plant-
derived compounds against Trypanosoma cruzi, the etiologic agent of Chagas' disease. In …

Vicenin 2, isolated from a traditionally used medicinal plant Artemisia capillaris, is a 6, 8-di-C-
glucoside of apigenin which has been previously reported to possess a wide variety of …

Endemic in 149 tropical and subtropical countries, neglected tropical diseases (NTDs) affect
more than 1 billion people annually with over 500,000 deaths. Among the NTDs, some of the …

Lychnophora ericoides Mart.(Asteraceae, Vernonieae) is a plant, endemic to Brazil, with
occurrence restricted to the “cerrado” biome. Traditional medicine employs alcoholic and …